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Ann Thorac Surg 2005;80:1032
© 2005 The Society of Thoracic Surgeons

Original article: General thoracic

Invited commentary

Akira Iyoda, MD, PhD

Department of Thoracic Surgery, Chiba University Graduate School of Medicine, 1-8-1, Inohana, Chuo-ku, Chiba 260-8670, Japan

(Email: iyoda@haibyo1.m.chiba-u.ac.jp).

The first 20% of the full text of this article appears below.

Embryonic proteins possibly play a significant role in the development of lung carcinomas. Bone morphogenetic protein-2 (BMP-2), a multipurpose cytokine, is a member of the transforming growth factor-ß superfamily. It is involved in the proliferation and differentiation of cells, and the regulation of cell adhesion. The BMP-2 contributes not only to bone formation, but also to neural and cardiac development. The BMP-2 may also be associated with tumor growth in malignant . . . [Full Text of this Article]






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