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Ann Thorac Surg 2003;75:773-774
© 2003 The Society of Thoracic Surgeons
Division of Cardiothoracic Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, 110 Francis St, No. LMOB Suite 2A, Boston, MA 02215, USA
e-mail: fsellke@caregroup.harvard.edu
| The first 20% of the full text of this article appears below. |
The study by Nishida and colleagues complements other studies published by this group and that of other groups which have examined the effects of implantation of bone marrow cells into the ischemic myocardium or ischemic hind limb of rats. The distinguishing aspect of the present study is that a novel method was used to create ischemic but not infarcted tissue. The authors used a thin copper wire as a guide to place a ligature around the left anterior descending coronary artery. The authors contend that this produced a stenotic but open vessel.
Most prior studies in rodent models of ischemia have
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