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Ann Thorac Surg 2005;79:757-766
© 2005 The Society of Thoracic Surgeons


Original article: Cardiovascular

CryoLife-O'Brien Stentless Valve: 10-Year Results of 402 Implants

Mark F. O'Brien, FRACSa,*, Michael A.H. Gardner, FRACSa, Bruce Garlick, FRACSa, Homayoun Jalali, MDa, Julie A. Gordon, RNa, Sarah L. Whitehouse, PhDb, Wendy E. Strugnell, BAppScc, Richard Slaughter, FRANZCRc

a Department of Cardiac Surgery, Brisbane, Australia
c Department of Medical Imaging, The Prince Charles Hospital and St Andrew's War Memorial Hospital, Brisbane, Australia
b Orthopaedic Research and Statistics Unit, Queensland University of Technology, Brisbane, Australia

Accepted for publication August 23, 2004.

* Address reprint requests to Dr O'Brien, 37/3482 Main Beach Parade, Main Beach Qld 4217, Australia (E-mail: drmfobrien{at}bigpond.com).

BACKGROUND: This truly stentless porcine valve is composite, without Dacron, and implanted supra-annularly. Ten-year analysis with magnetic resonance imaging is presented.

METHODS: From 1992 to 2002, 402 patients (mean 73.5 years) had aortic valve replacement. Associated procedures were required in 252 patients (63%). Serial echoes provided 1340 studies. Clinical follow-up was 100%. Magnetic resonance imaging focused on aortic annulus extensibility.

RESULTS: The 30-day mortality was 0.99% (4 deaths). Morbidity comprised thromboembolism (40 patients including 18 patients with permanent strokes); endocarditis (9 patients); and reoperation (9 patients [periprosthetic leak, 2; endocarditis, 5; technical needle damage, 1; and structural degeneration, 1]). Of 402 valves more than 10 years, five valves were explanted, one only for structural failure. Except for endocarditis (2 patients), no late deaths (69 patients, 1.5 months to 5.7 years) were valve related. Echocardiography demonstrated low gradients with good orifice areas, excellent ventricular regression (p = 0.0001 preoperative and postoperative comparisons) and late incompetence (mild in 45 patients and moderate in 9 patients). No living patient has severe incompetence. Magnetic resonance imaging demonstrated the annulus ‘expanding and relaxing’ throughout the cardiac cycle, the mean increase in cross-sectional area being 37%, resembling normal aortic root dynamics.

CONCLUSIONS: Elderly patients received this hemodynamically acceptable valve with its simple, supra-annular implantation and satisfactory mid-term morbid-free lifestyle to 10 years maximum follow-up. With only one structural failure, restoration of valve annular extensibility may have a favorable influence on long-term durability.




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