ATS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Author home page(s):
Federico Venuta
Tiziano de Giacomo
Erino A. Rendina
Anna Maria Ciccone
Marco Anile
Giorgio F. Coloni
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Venuta, F.
Right arrow Articles by Coloni, G. F.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Venuta, F.
Right arrow Articles by Coloni, G. F.
Related Collections
Right arrow Lung - other

Ann Thorac Surg 2005;79:411-416
© 2005 The Society of Thoracic Surgeons

Original article: General thoracic

Bronchoscopic Lung-Volume Reduction With One-Way Valves in Patients With Heterogenous Emphysema

Federico Venuta, MDa,*, Tiziano de Giacomo, MDa, Erino A. Rendina, MDa, Anna Maria Ciccone, MDa, Daniele Diso, MDa, Alessandro Perrone, MDb, Daniela Parola, MDb, Marco Anile, MDa, Giorgio F. Coloni, MDa

a Department of Thoracic Surgery, University of Rome "La Sapienza," Rome, Italy
b Department of Pulmonology, University of Rome "La Sapienza," Rome, Italy

Accepted for publication July 19, 2004.

* Address reprint requests to Dr Venuta, University of Rome "La Sapienza," Department of Thoracic Surgery, Policlinico Umberto I, V.le del Policlinico, 00100 Rome, Italy (E-mail: sofed{at}libero.it).

BACKGROUND: We evaluated the feasibility and short-term functional outcome after bronchoscopic lung-volume reduction performed with one-way valves in patients with severe heterogeneous emphysema.

METHODS: Thirteen patients entered this pilot study. Endobronchial one-way valves were placed in the segmental bronchi supplying the most hyperinflated parts of the emphysematous lungs to allow lung deflation, reduce lung volume, and alleviate symptoms. The valves and delivery catheter were inserted under intravenous anesthesia and spontaneous assisted ventilation, with visual control through a flexible bronchoscope. We performed unilateral bronchoscopic lung-volume reduction in 11 patients and staged bilateral procedures in 2. Preoperative median forced expiratory volume in 1 second (FEV1) was 0.75 L/s (22%), residual volume was 5.3 L (233%), total lung capacity, 7.9 L (123%); intrathoracic gas volume, 6.5 L (176%); and 6-minute walk test, 223 meters. All patients required supplemental oxygen at rest (1.4 L/min). The median preoperative Medical Research Council (MRC) scale dyspnea score was 4.

RESULTS: Six complications occurred in 3 patients: two bilateral and one contralateral pneumothorax, one pneumonia, and two episodes of bronchospasm. Functional results at 1 and 3 months showed a significant improvement in FEV1, residual volume, and 6-minute walk test; 43% of the patients were able to completely stop supplemental oxygen. The posttreatment MRC median dyspnea score at 1 and 3 months was 2. Bronchoscopic follow up at 1 and 3 months showed that the valves were correctly in place with no granulation.

CONCLUSIONS: Bronchoscopic lung-volume reduction with one-way valves can be performed with acceptable short-term safety and worthwhile functional benefits.




This article has been cited by other articles:


Home page
 Eur Respir JHome page
H. O. Coxson, P. V. Nasute Fauerbach, C. Storness-Bliss, N. L. Muller, S. Cogswell, D. H. Dillard, C. L. Finger, and S. C. Springmeyer
Computed tomography assessment of lung volume changes after bronchial valve treatment
Eur. Respir. J., December 1, 2008; 32(6): 1443 - 1450.
[Abstract] [Full Text] [PDF]

Home page
 Proc Am Thorac SocHome page
E. P. Ingenito, D. E. Wood, and J. P. Utz
Bronchoscopic Lung Volume Reduction in Severe Emphysema
Proceedings of the ATS, May 1, 2008; 5(4): 454 - 460.
[Abstract] [Full Text] [PDF]

Home page
 MMCTSHome page
F. Venuta, E. A. Rendina, T. De Giacomo, and G. F. Coloni
Bronchoscopic lung volume reduction
MMCTS, December 17, 2007; 2007(1217): 2121.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
P. F.G. Cardoso, G. I. Snell, P. Hopkins, G. W. Sybrecht, G. Stamatis, A. W. Ng, and P. Eng
Clinical application of airway bypass with paclitaxel-eluting stents: Early results.
J. Thorac. Cardiovasc. Surg., October 1, 2007; 134(4): 974 - 981.
[Abstract] [Full Text] [PDF]

Home page
 Eur Respir JHome page
P. Bhattacharyya, D. Sarkar, S. Nag, S. Ghosh, and S. Roychoudhury
Transbronchial decompression of emphysematous bullae: a new therapeutic approach
Eur. Respir. J., May 1, 2007; 29(5): 1003 - 1006.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
D. E. Wood, R. J. McKenna Jr, R. D. Yusen, D. H. Sterman, D. E. Ost, S. C. Springmeyer, H. X. Gonzalez, M. S. Mulligan, T. Gildea, W. V. Houck, et al.
A multicenter trial of an intrabronchial valve for treatment of severe emphysema
J. Thorac. Cardiovasc. Surg., January 1, 2007; 133(1): 65 - 73.
[Abstract] [Full Text] [PDF]

Home page
 ERRHome page
M. I. Polkey and N. S. Hopkinson
Bronchoscopic lung volume reduction
Eur. Respir. Rev., December 1, 2006; 15(100): 99 - 103.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
M. Anile, F. Venuta, T. De Giacomo, E. A. Rendina, D. Diso, F. Pugliese, F. Ruberto, and G. F. Coloni
Treatment of persistent air leakage with endobronchial one-way valves.
J. Thorac. Cardiovasc. Surg., September 1, 2006; 132(3): 711 - 712.
[Full Text] [PDF]

Home page
 ChestHome page
H. G. de Oliveira, A. V. Macedo-Neto, A. B. John, S. Jungblut, J. C. Prolla, S. S. Menna-Barreto, and E. A. F. Fortis
Transbronchoscopic Pulmonary Emphysema Treatment: 1-Month to 24-Month Endoscopic Follow-up.
Chest, July 1, 2006; 130(1): 190 - 199.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
D. Feller-Kopman, R. Bechara, R. Garland, A. Ernst, and S. Ashiku
Use of a removable endobronchial valve for the treatment of bronchopleural fistula.
Chest, July 1, 2006; 130(1): 273 - 275.
[Abstract] [Full Text] [PDF]

Home page
 ThoraxHome page
E J Cetti, A J Moore, and D M Geddes
Collateral ventilation
Thorax, May 1, 2006; 61(5): 371 - 373.
[Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
F. Venuta, E. A. Rendina, T. De Giacomo, M. Anile, D. Diso, C. Andreetti, F. Pugliese, and G. F. Coloni
Bronchoscopic procedures for emphysema treatment
Eur. J. Cardiothorac. Surg., March 1, 2006; 29(3): 281 - 287.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
I. Y. P. Wan, T. P. Toma, D. M. Geddes, G. Snell, T. Williams, F. Venuta, and A. P. C. Yim
Bronchoscopic Lung Volume Reduction for End-Stage Emphysema: Report on the First 98 Patients
Chest, March 1, 2006; 129(3): 518 - 526.
[Abstract] [Full Text] [PDF]

Home page
 BMJHome page
F. Venuta and G. Bognolo
Surgery for emphysema.
BMJ, February 18, 2006; 332(7538): 375 - 376.
[Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
N. S. Hopkinson and M. I. Polkey

Am. J. Respir. Crit. Care Med., January 15, 2006; 173(2): 248a - 249.
[Full Text] [PDF]

Home page
 Proc Am Thorac SocHome page
T. K. Trow
Clinical Year in Review I: Lung Cancer, Interventional Pulmonology, Noninvasive Mask Ventilation, and Pulmonary Vascular Disease
Proceedings of the ATS, August 1, 2005; 2(2): 102 - 104.
[Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 2005 by The Society of Thoracic Surgeons.