ATS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Yamamoto, K.
Right arrow Articles by Kamura, T.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Yamamoto, K.
Right arrow Articles by Kamura, T.
Related Collections
Right arrow Lung - other

Ann Thorac Surg 2004;77:1179-1182
© 2004 The Society of Thoracic Surgeons

Original article: general thoracic

Pulmonary metastasectomy for uterine cervical cancer: a multivariate analysis

Kaichiro Yamamoto, MD, PhDa*, Hiroyuki Yoshikawa, MD, PhDb, Kenji Shiromizu, MD, PhDc, Toshiaki Saito, MD, PhDd, Kazuo Kuzuya, MD, PhDe, Ryuichiro Tsunematsu, MD, PhDf, Toshiharu Kamura, MD, PhDg

a Department of Obstetrics and Gynecology, Sakai Hospital, Kinki University School of Medicine, Osaka, Japan
b Department of Obstetrics and Gynecology, University of Tsukuba, Ibaraki, Japan
c Saitama Cancer Center, Saitama, Japan
d National Kyushu Cancer Center, Fukuoka, Japan
e Aichi Cancer Center Hospital, Aichi, Japan
f National Cancer Center, Tokyo, Japan
g Kurume University Hospital, Fukuoka, Japan

Accepted for publication June 13, 2003.

* Address reprint requests to Dr Yamamoto, Department of Obstetrics and Gynecology, Sakai Hospital, Kinki University School of Medicine, 2-7-1, Harayamadai, Sakai, Osaka 590-0132, Japan
e-mail: yamamoto{at}sakai.med.kindai.ac.jp

BACKGROUND: This study evaluated the results of resection of pulmonary metastases from cervical cancer.

METHODS: A total of 7,748 patients with primary stage Ib or II cervical cancer underwent curative initial treatment consisting of radical hysterectomy or radiotherapy in 22 hospitals. Of the 7,748 patients, 29 (0.37%) patients had pulmonary metastases, which were detected after a disease-free period after initial treatment (radical hysterectomy or radiotherapy) and were resected with the intention to cure by June 30, 1998.

RESULTS: The 5-year disease-free survival rate after pulmonary metastasectomy for all patients was 32.9%. Patients with one or two pulmonary metastases had a 5-year disease-free survival rate of 42.2% compared with 0% for patients with three or four metastases (p = 0.0003). Patients with squamous cell cancers had a 5-year disease-free survival rate of 47.4% compared with 0% for patients with adenosquamous cell cancers or adenocarcinoma (p = 0.0141). On multivariate analysis, the significant prognostic variables for disease-free survival were two or fewer metastases (p = 0.0232) and squamous cell cancer (p = 0.0168).

CONCLUSIONS: Cervical cancer patients with pulmonary metastases after initial treatment (radical hysterectomy or radiotherapy) could expect to achieve long-term disease-free survival by pulmonary metastasectomy when there are two or fewer metastases diagnosed as squamous cell cancer.




This article has been cited by other articles:


Home page
 Ann. Thorac. Surg.Home page
J. M. Clavero, C. Deschamps, S. D. Cassivi, M. S. Allen, F. C. Nichols III, B. A. Barrette, D. R. Larson, and P. C. Pairolero
Gynecologic Cancers: Factors Affecting Survival After Pulmonary Metastasectomy
Ann. Thorac. Surg., June 1, 2006; 81(6): 2004 - 2007.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 2004 by The Society of Thoracic Surgeons.