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Ann Thorac Surg 2001;71:S249-S252
© 2001 The Society of Thoracic Surgeons


Valvular bioprostheses over 15 years

Experience with the 19-mm Carpentier-Edwards pericardial bioprosthesis in the elderly

Michel Carrier, MDa, Michel Pellerin, MDa, Louis P. Perrault, MD, PhDa, Yves Hébert, MDa, Pierre Pagé, MDa, Raymond Cartier, MDa, Ihor Dyrda, MDa, L. Conrad Pelletier, MDa

a Department of Surgery and Medicine, Montreal Heart Institute, and the University of Montreal, Montreal, Quebec, Canada

Address reprint requests to Dr Carrier, Department of Surgery, Montreal Heart Institute, Research Center, 5000 Belanger St East, Montreal, PQ, Canada H1T 1C8
e-mail: carrier{at}icm.umontreal.ca

Presented at the VIII International Symposium on Cardiac Bioprostheses, Cancun, Mexico, Nov 3–5, 2000.

Background. Valve replacement in small aortic root remains a surgical challenge. The objective of this study was to compare results of the 19-mm bioprosthesis with those of larger prostheses in the elderly.

Methods. The 443 patients, 70 years of age and older, who underwent aortic valve replacement with Carpentier-Edwards pericardial bioprostheses were reviewed.

Results. There were 93 patients with a mean age of 76 ± 4 years with implantation of 19-mm prostheses and 350 patients with a mean age of 75 ± 4 years with larger bioprostheses. Associated aortoplasty was performed in 10 patients (11%) with 19-mm bioprostheses and in 8 patients (2%) with larger bioprostheses (p = 0.001). There were 11 deaths (12%) within 30 days of surgery in patients with 19-mm prostheses and 22 deaths (6%) among those with larger prostheses (p = 0.1). The 7-year survival rate averaged 61% ± 7% in patients with 19-mm prostheses and 67% ± 4% in those with larger prostheses (p = 0.8). The 7-year freedom rates from all valve-related events averaged 96% ± 2% and 93% ± 2%, respectively (p = 0.6).

Conclusions. Aortic valve replacement with the 19-mm Carpentier-Edwards pericardial bioprosthesis offers excellent midterm results in the elderly.







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