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Ann Thorac Surg 1998;66:S12-S16
© 1998 The Society of Thoracic Surgeons
a Division of Cardiothoracic Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA
Address reprint requests to Dr Edmunds, Division of Cardiothoracic Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA 19104
Presented at "Risk Management in CABG: Significant Surgical Considerations," New Orleans, LA, Jan 24, 1998.
This article reviews the roles of the contact and complement systems and of neutrophils and monocytes in the inflammatory response to cardiopulmonary bypass and open heart operation. These blood proteins and cells, together with other blood elements, produce the vasoactive and cytotoxic substances and microemboli that cause the morbidity associated with cardiopulmonary bypass and open heart operation.
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