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Ann Thorac Surg 1998;66:402-411
© 1998 The Society of Thoracic Surgeons


Original articles: cardiovascular

Operation for acute and chronic aortic dissection: recent outcome with regard to neurologic deficit and early death

Hazim J. Safi, MDa, Charles C. Miller, III, PhDa, Michael J. Reardon, MDa,a, Dimitrios C. Iliopoulos, MDa, George V. Letsou, MDa, Rafael Espada, MDa, John C. Baldwin, MDa

a Department of Surgery, The Methodist Hospital and Baylor College of Medicine, Houston, Texas, USA

Address reprint requests to Dr Safi, 6550 Fannin, Suite 1603, Houston, TX 77030

Presented at the Forty-fourth Annual Meeting of the Southern Thoracic Surgical Association, Naples, FL, Nov 6–8, 1997.

Background. We reviewed our experience in the repair of acute and chronic aortic dissection with regard to early neurologic deficit and death.

Methods. Between February 1991 and June 1996, we performed 206 operations on 195 patients for aortic dissection. Ascending or arch repair, or a combination (type A dissection) was performed on 92 of 206 patients (45%); 44 of 92 (48%) were acute dissection and 48 of 92 (52%) were chronic. Descending or thoracoabdominal repair (type B dissection) was performed on 114 of 206 patients (55%); 22 of 114 (19%) were acute and 92 of 114 (81%) were chronic.

Results. Among type A cases, strokes occurred in 6 of 92 patients (7%) overall; 4 of 44 (9%) were acute cases and 2 of 48 (4%) were chronic (p < 0.34). Early deaths for type A were 11 of 92 (12%) overall; 9 of 44 (20%) acute and 2 of 48 (4%) chronic (p < 0.02). In type B cases, neurologic complications were 15 of 114 (13%) overall; 7 of 22 (32%) were acute cases and 8 of 92 (9%) were chronic (p < 0.004). Early deaths for type B were 12 of 114 (11%) overall; 3 of 22 (14%) acute and 9 of 92 (10%) chronic (p < 0.6). Preoperative hypotension was significant in acute type A patients, with strokes in 2 of 7 (29%) hypotensives compared with 2 of 37 (5%) normotensives (p < 0.05) and early death in 4 of 7 (57%) hypotensives versus 5 of 37 (14%) normotensives (p < 0.009).

Conclusions. Morbidity and mortality for repair of chronic dissection types A and B were acceptable. Preoperative hypotension in acute type A dissection was a major predisposing factor toward stroke (29% versus 5%, p < 0.05). Acute type B dissection had acceptable mortality (14%) but a high rate of neurologic complications (32%).




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