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Francesco Musumeci
Vinayak Shukla
Carmelo Mignosa
Giovanni Casali
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Ann Thorac Surg 1996;62:486-488
© 1996 The Society of Thoracic Surgeons

Original Articles: Cardiovascular

Early Repair of Postinfarction Ventricular Septal Defect With Gelatin-Resorcin-Formol Biological Glue

Francesco Musumeci, MD, Vinayak Shukla, MD, Carmelo Mignosa, MD, Giovanni Casali, MD, Shahid Ikram, MD

Department of Cardiac Surgery, University Hospital of Wales, Cardiff, United Kingdom

Accepted for publication March 18, 1996.

Background. Early surgical repair of postinfarction ventricular septal defect has improved early mortality rate. Mortality remains high in patients presenting within 1 week of infarction, or when rupture has occurred in the inferior part of the septum.

Methods. We describe a surgical technique for repair of postinfarction ventricular septal defect that involves no infarctectomy: continuous suturing of a bovine pericardial patch to healthy myocardium around the infarcted area and use of gelatin-resorcin-formol biological glue as a sealant between the patch and the interventricular septum.

Results. We have used this technique successfully in 3 consecutive patients in whom repair was performed within 1 week of myocardial infarction. The rupture of the interventricular septum was located anteriorly in 2 patients and inferiorly in the other. They all made an uneventful recovery, and at follow-up there was no evidence of residual shunt.

Conclusions. This technique can be a useful adjunct to the surgical management of this difficult group of patients.




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