HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Author home page(s): Masaaki Kato Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Kato, M. Articles by Ohnishi, K. Search for Related Content PubMed PubMed Citation Articles by Kato, M. Articles by Ohnishi, K. Related Collections Related Article

Ann Thorac Surg 1995;59:908-914
© 1995 The Society of Thoracic Surgeons

Experimental Assessment of Newly Devised Transcatheter Stent-Graft for Aortic Dissection

Division of Cardiovascular Surgery, Osaka Prefectural Hospital, and Department of Bioengineering, National Cardiovascular Center Research Institute, Osaka, Japan

Accepted for publication November 7, 1994.

Despite recent advances, surgical results for Stanford type B dissection are not yet satisfactory because the procedure is so highly invasive. The aim of this study was to devise a new intraaortic (IA) graft that would offer less invasive treatment for type B dissection. To close the entry of type B dissections using transcatheter placement, we devised an IA graft (inner diameter, 15--20 mm; length, 40 to 60 mm) in which a self-expandable stent was covered with a thin, open-cell--structured polyurethane jacket. In acute animal experiments in which type B aortic dissections were prepared in 4 mongrel dogs, IA grafts were implanted to close the entry using a transfemoral catheter sheath, and closure of all the entries was confirmed by aortography. In chronic experiments, five IA grafts for normal descending aortas and one IA graft for an experimentally dissected aorta were implanted to observe histologic biocompatibility for up to 8 months. Histopathologic examination conducted at the projected sacrifice periods revealed that endothelialization of the luminal surface of the IA graft had begun as early as 1 month after implantation and was completed within 4 months. The prototype device that we developed may be promising as an effective, minimally invasive therapeutic intervention for closure of the entry site of type B dissection.

Related Article

INVITED COMMENTARY

Michael D. Dake
Ann. Thorac. Surg. 1995 59: 914-915. [Extract] [Full Text]

This article has been cited by other articles:

				K. Shimamura, T. Kuratani, G. Matsumiya, M. Kato, Y. Shirakawa, H. Takano, N. Ohta, and Y. Sawa Long-term results of the open stent-grafting technique for extended aortic arch disease. J. Thorac. Cardiovasc. Surg., June 1, 2008; 135(6): 1261 - 1269. [Abstract] [Full Text] [PDF]

				S.-G. Kang, D. Y. Lee, M. Maeda, E. S. Kim, D. Choi, B.-O. Kim, H. K. Yoon, K. B. Sung, and H.-Y. Song Aortic Dissection: Percutaneous Management with a Separating Stent-Graft—Preliminary Results Radiology, August 1, 2001; 220(2): 533 - 539. [Abstract] [Full Text] [PDF]

				B. V. Czermak, P. Waldenberger, G. Fraedrich, A. H. Dessl, K. E. Roberts, R. J. Bale, R. Perkmann, and W. R. Jaschke Treatment of Stanford Type B Aortic Dissection with Stent-Grafts: Preliminary Results Radiology, November 1, 2000; 217(2): 544 - 550. [Abstract] [Full Text]

				T. Ohata, T. Sakakibara, H. Takano, H. Izutani, and Y. Inoue Rapid enlargement of a distal arch aneurysm after endovascular stent-grafting for pseudoaneurysm: Case report J. Thorac. Cardiovasc. Surg., October 1, 2000; 120(4): 824 - 826. [Full Text] [PDF]

				B. J. d’Othee, H. Rousseau, P. Soula, B. Dongay, M. I. Millan, M. Galinier, P. Massabuau, F. Joffre, and P. Otal AORTIC STENT GRAFTING AND SIDE-BRANCH EMBOLIZATION IN AN EXPANDING CHRONIC TYPE B DISSECTION J. Thorac. Cardiovasc. Surg., December 1, 1999; 118(6): 1021 - 1025. [Abstract] [Full Text] [PDF]

				M. Ezure, Y. Kotsuka, A. Furuse, M. Kawauchi, T. Kohno, and H. Kubota Repair of Ruptured Anastomotic Aneurysm: Elephant Trunk Technique After Endovascular Covered Stents Ann. Thorac. Surg., January 1, 1998; 65(1): 241 - 241. [Abstract] [Full Text] [PDF]

				M. Kato, H.-z. Bai, K. Sato, S. Kawamoto, M. Kaneko, T. Ueda, D. Kishi, and K. Ohnishi Determining Surgical Indications for Acute Type B Dissection Based on Enlargement of Aortic Diameter During the Chronic Phase Circulation, November 1, 1995; 92(9): 107 - 112. [Abstract] [Full Text]