HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by McDonald, M. L. Articles by Pairolero, P. C. Search for Related Content PubMed PubMed Citation Articles by McDonald, M. L. Articles by Pairolero, P. C.

The Annals of Thoracic Surgery, Vol 58, 1599-1602, Copyright © 1994 by The Society of Thoracic Surgeons

ARTICLES

Pulmonary resection for metastatic breast cancer

ML McDonald, C Deschamps, DM Ilstrup, MS Allen, VF Trastek and PC Pairolero
Section of General Thoracic Surgery, Mayo Clinic, Rochester, Minnesota 55905.

Between 1982 and 1992, 60 consecutive female patients underwent pulmonary resection for metastatic breast carcinoma. Median age was 58 years (range, 21 to 81 years). The median tumor-free interval after primary breast cancer operation was 2.2 years (range, 7 days to 20.6 years). Thirty-one patients (51.6%) had solitary pulmonary metastases. Forty patients (66.7%) had complete pulmonary resection, which consisted of wedge excision in 33, lobectomy in 6, and pneumonectomy in 1. The remaining 20 patients had incomplete resection, which consisted of wedge excision in all. Altogether, 8 patients (13.3%) had development of postoperative complications, which included pneumothorax, prolonged air leak, pulmonary embolism, retained secretions requiring bronchoscopy, atrial fibrillation, and chest tube site infection. There was one operative death (1.7%). Follow-up was complete in all patients and ranged from 23 days to 10.7 years (median, 3.5 years). Recurrence developed in 32 of the 39 survivors (82.1%) who had complete resection. Median disease-free interval after lung resection was 1.6 years (range, 23 days to 9.3 years). Overall 5-year survival was 37.8% (95% confidence interval, 25.1% to 50.5%). The 40 patients who had complete resection had a 5-year survival of 35.6% (95% confidence interval, 20.4% to 50.8%) as compared with 42.1% (95% confidence interval, 19.0% to 65.3%) for the 20 patients with incomplete resection (p = not significant). Although pulmonary resection is safe, we could not demonstrate improved survival after complete pulmonary resection of metastatic breast carcinoma in this highly selected group of patients.

This article has been cited by other articles:

				A. Monteiro, N. Arce, J. Bernardo, L. Eugenio, and M. J. Antunes Surgical resection of lung metastases from epithelial tumors Ann. Thorac. Surg., February 1, 2004; 77(2): 431 - 437. [Abstract] [Full Text] [PDF]

				S. E. Singletary, G. Walsh, J.-N. Vauthey, S. Curley, R. Sawaya, K. L. Weber, F. Meric, and G. N. Hortobagyi A Role for Curative Surgery in the Treatment of Selected Patients with Metastatic Breast Cancer Oncologist, June 1, 2003; 8(3): 241 - 251. [Abstract] [Full Text] [PDF]

				G. Friedel, U. Pastorino, R. J. Ginsberg, P. Goldstraw, M. Johnston, H. Pass, J. B. Putnam, and H. Toomes Results of lung metastasectomy from breast cancer: prognostic criteria on the basis of 467 cases of the international registry of lung metastases Eur. J. Cardiothorac. Surg., September 1, 2002; 22(3): 335 - 344. [Abstract] [Full Text] [PDF]

				J. B. Zwischenberger and S. K. Alpard Pulmonary metastasectomy Ann. Thorac. Surg., July 1, 1999; 68(1): 287 - 288. [Full Text] [PDF]

				M. Kamiyoshihara, T. Hirai, O. Kawashima, and Y. Morishita Resection of pulmonary metastases in six patients with disease-free interval greater than 10 years Ann. Thorac. Surg., July 1, 1998; 66(1): 231 - 233. [Abstract] [Full Text] [PDF]

				A. Bernard Resection of Pulmonary Nodules Using Video-Assisted Thoracic Surgery Ann. Thorac. Surg., January 1, 1996; 61(1): 202 - 204. [Abstract] [Full Text]