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The Annals of Thoracic Surgery, Vol 58, 1096-1102, Copyright © 1994 by The Society of Thoracic Surgeons
A Serraf, L Houyel, F Nicolas, F Lacour-Gayet, J Bruniaux, J Petit, MS Uva, D Roux and C Planche
The outcome of Fontan-type procedures is dependent on several risk factors,
among which pulmonary vascular resistances (PVRs) are an important
component. Preoperative calculation of PVR entails several potential
sources of error, particularly in patients with pulmonary atresia or
multiple sources of pulmonary blood flow. In an attempt to develop a
reliable test that accurately assesses the hemodynamic patterns of the
pulmonary vascular bed before a Fontan procedure, a simulation of
Fontan-type circulation was achieved in 13 patients by a partial
cardiopulmonary bypass between the main pulmonary artery and both venae
cavae (cavopulmonary bypass). During cavopulmonary bypass, pressures and
resistances were recorded. Immediately after cavopulmonary bypass, the
circulation was converted to standard cardiopulmonary bypass and the
cavopulmonary connection was carried out. Preoperative pulmonary vascular
resistance indexes were assessed roughly by the arteriovenous oxygen
difference in systemic and pulmonary beds. There was no correlation between
preoperative and perioperative calculations of pulmonary vascular
resistance indexes (r = 0.24; p = not significant). Hemodynamic data
available for all patients then were correlated to the early postoperative
outcome assessed by a subjective four-point scale. A positive, significant
correlation was found with intraoperative PVR (r = 0.90; p < 0.001),
indexed PVR (r = 0.90; p < 0.001), and the pulmonary to systemic
vascular resistance ratio (r = 0.98; p < 0.0001). Two of 13 patients had
a 4-mm fenestration in the atrial baffle. No mortality or morbidity was
related to the procedure. The absolute values of PVR and pulmonary vascular
resistance indexes were strikingly higher than generally admitted for this
type of procedure.(ABSTRACT TRUNCATED AT 250 WORDS)
ARTICLES
Pulmonary circulation evaluation before cavopulmonary connections: the cavopulmonary bypass
Department of Pediatric Cardiac Surgery, Marie-Lannelongue Hospital, Le Plessis-Robinson, France.
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