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The Annals of Thoracic Surgery, Vol 56, 387-389, Copyright © 1993 by The Society of Thoracic Surgeons


ARTICLES

Intraoperative procurement of autologous fibrin glue

RL Quigley, JA Perkins, RJ Gottner, RD Curran, BE Kuehn, WJ Hoff, ME Wallock, CE Arentzen and JC Alexander Jr
Department of Surgery, Northwestern University, Evanston Hospital, Illinois 60201.

A method of intraoperative procurement of autologous fibrin glue is described. The relative efficacy of our autologous preparation is compared with that of fibrin glue made with homologous cryoprecipitate. Experimentally, the fibrinogen content and the strength are less than those found in cryoprecipitate and appear related to the fibrinogen content of the autologous plasma used as substrate in the fibrin glue reaction. Clinically, no significant differences are noted in the performance of autologous fibrin glue. We believe the absence of the risk of blood-borne infection with the autologous product is a major advantage.


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