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The Annals of Thoracic Surgery, Vol 55, 1197-1201, Copyright © 1993 by The Society of Thoracic Surgeons

ARTICLES

Massive thymic hyperplasia

AG Linegar, JA Odell, WM Fennell, PM Close, MK De Groot, DR Casserly and JI Perold
Department of Cardiothoracic Surgery, University of Cape Town, South Africa.

Massive thymic hyperplasia is an extremely rare form of true thymic hyperplasia most often described in infants and children. Hyperplasia of this order is not known to occur in any other organ, and its etiology and prognostic significance remain unknown. As there is no accurate way of preoperatively differentiating massive thymic hyperplasia from other tumors of the thymus and anterior mediastinum, we advise excision in all cases for histological analysis and relief of mediastinal compression. This description of 4 cases updates the 30 previously reported cases, and includes a literature review.




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Copyright © 1993 by The Society of Thoracic Surgeons.