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The Annals of Thoracic Surgery, Vol 55, 876-882, Copyright © 1993 by The Society of Thoracic Surgeons
MR Johnson, MR Costanzo-Nordin, AL Heroux, WG Kao, GM Mullen, R Pifarre and HJ Sullivan
To determine if high-risk heart operation with circulatory support standby
is an acceptable alternative to direct heart transplantation, we reviewed
21 patients who were accepted as heart transplant candidates but offered a
heart operation because of the availability of circulatory support.
Preoperative left ventricular ejection fraction was 0.25 +/- 0.08 (mean +/-
standard deviation), and New York Heart Association functional class was
3.4 +/- 0.7. The patients underwent 16 bypass graft operations, 4 mitral
and 2 aortic valve replacements, and 4 defibrillator implantations
(combined procedures in 5 patients). An intraaortic balloon pump was placed
in 12 patients. One patient required biventricular assist device support
but was weaned in 11 days. Twenty patients were discharged 14.8 +/- 11.5
days postoperatively. One patient died 15 days postoperatively of
amiodarone-induced respiratory failure, and 1 died suddenly 2 months
postoperatively. At 10.5 +/- 6 months postoperatively, 19 patients (90%)
are alive. Mean functional class is 1.9 +/- 0.9. None of the patients has
undergone transplantation, but 2 are awaiting donor organs. We conclude
that in selected heart transplant candidates high-risk heart operation is a
viable alternative to direct heart transplantation.
ARTICLES
High-risk cardiac operation: a viable alternative to heart transplantation
Department of Medicine, Loyola University of Chicago, Maywood, Illinois 60153.
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