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The Annals of Thoracic Surgery, Vol 55, 855-858, Copyright © 1993 by The Society of Thoracic Surgeons
GR Daicoff, LM Botero and JA Quintessenza
Between February 1986 and April 1992, 27 patients ranging in age from 8 to
65 years (median, 18 years) underwent allograft replacement of the aortic
valve with one death (operative mortality, 3.7%). The indications for
operation were aortic regurgitation in 14 patients, aortic stenosis in 7,
aortic stenosis/regurgitation in 4, and endocarditis in 2. Associated
lesions included annuloectasia in 4 patients (1 with Marfan's syndrome),
sinus of Valsalva aneurysm in 3, coronary artery disease in 4, and
ventricular septal defect in 2. The freehand technique was used in 12
patients and the miniroot replacement in 15 patients. The postoperative
transvalvular gradient was 17 mm Hg in freehand valves and 7 mm Hg in the
miniroot valves. Initial postoperative study showed no or trivial aortic
regurgitation in all 26 survivors except 1 freehand patient who had mild
aortic regurgitation. At late study up to 6 years postoperatively all 10 of
our available freehand patients showed progressive regurgitation, and it
was severe in 4 patients. By contrast only half of the miniroot patients
showed progressive regurgitation, and in none was it severe. Allograft
replacement of the aortic valve can be done in children and adults with low
mortality rate, short hospital stay, and excellent early function.
Subsequent follow-up studies suggest that the miniroot replacements are
superior to the freehand valves with lower transvalvular gradients, less
valvular regurgitation, and delayed progression of valvular regurgitation.
ARTICLES
Allograft replacement of the aortic valve versus the miniroot and valve
Department of Cardiac Services, All Children's Hospital, St. Petersburg, Florida.
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