HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Shiiya, N. Articles by Loisance, D. Y. Search for Related Content PubMed PubMed Citation Articles by Shiiya, N. Articles by Loisance, D. Y.

The Annals of Thoracic Surgery, Vol 53, 1074-1079, Copyright © 1992 by The Society of Thoracic Surgeons

ARTICLES

Changes in hemodynamics and coronary blood flow during left ventricular assistance with the Hemopump

N Shiiya, R Zelinsky, PH Deleuze and DY Loisance
Centre de Recherches Chirurgicales, CHU Henri Mondor, Creteil, France.

The Hemopump, a catheter-mounted left ventricular assist device, has been demonstrated to be effective in supporting patients with potentially reversible cardiac failure. The mechanism of recovery of the hearts with this device is not fully understood. The effects of the Hemopump on hemodynamics and coronary blood flow with and without myocardial ischemia and failure have been studied in 8 anesthetized open-chest dogs. Coronary blood flow in the left circumflex artery was assessed with an intracoronary Doppler catheter. Myocardial ischemia was induced by ligation of the left anterior descending and diagonal branches. The effects of maximum support were compared with those of minimum support. The effects of the Hemopump varied according to cardiac function. When cardiac dysfunction was mild, the Hemopump support slightly reduced myocardial O2 demand (assessed by pressure- work index) by volume unloading. When cardiac dysfunction was severe, total bypass was achieved and myocardial O2 demand decreased by 45%, owing to both volume and pressure unloading. Coronary blood flow was incompletely auto-regulated, and the ratio of blood flow to O2 demand increased.

This article has been cited by other articles:

				B. Meyns, R. Autschbach, A. Boning, W. Konertz, K. Matschke, F. Schondube, K. Wiebe, and E. Fischer Coronary artery bypass grafting supported with intracardiac microaxial pumps versus normothermic cardiopulmonary bypass: a prospective randomized trial Eur. J. Cardiothorac. Surg., July 1, 2002; 22(1): 112 - 117. [Abstract] [Full Text] [PDF]

				J. M Toomasian and W. Aboul-Hosn Coronary artery bypass grafting using a miniature right ventricular support system Perfusion, December 1, 2000; 15(6): 521 - 526. [Abstract] [PDF]

				B. Meyns, P. Sergeant, T. Nishida, B. Perek, M. Zietkiewicz, and W. Flameng Micropumps to support the heart during CABG Eur. J. Cardiothorac. Surg., February 1, 2000; 17(2): 169 - 174. [Abstract] [Full Text] [PDF]

				B Meyns, P Sergeant, T Siess, M Zietkiewicz, B Perek, Y Nishida, and W Flameng Coronary artery bypass graft with biventricular microaxial pumps Perfusion, July 1, 1999; 14(4): 287 - 290. [PDF]

				B Meyns, S Ozaki, P Sergeant, Y Nishimura, and W Flameng Circulatory support during minimally invasive coronary surgery Perfusion, July 1, 1998; 13(4): 265 - 271. [PDF]

				B. Meyns, Y. Nishimura, R. Racz, R. Jashari, and W. Flameng ORGAN PERFUSION WITH HEMOPUMP DEVICE ASSISTANCE WITH AND WITHOUT INTRAAORTIC BALLOON PUMPING J. Thorac. Cardiovasc. Surg., August 1, 1997; 114(2): 243 - 253. [Abstract] [Full Text]

				B. P. Meyns, P. T. Sergeant, W. J. Daenen, and W. J. Flameng Left Ventricular Assistance With the Transthoracic 24F Hemopump for Recovery of the Failing Heart Ann. Thorac. Surg., August 1, 1995; 60(2): 392 - 397. [Abstract] [Full Text]

				G. J. Cooper, D. Y. Loisance, M. Miyama, Y. Abe, and P. H. Deleuze Direct Mechanical Assistance of the Right Ventricle With the Hemopump in a Porcine Model Ann. Thorac. Surg., February 1, 1995; 59(2): 443 - 447. [Abstract] [Full Text]