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The Annals of Thoracic Surgery, Vol 53, 635-641, Copyright © 1992 by The Society of Thoracic Surgeons
DA Haydock, EP Trulock, LR Kaiser, SR Knight, MK Pasque and JD Cooper
In a series of 34 lung transplant patients, donor lung dysfunction occurred
on 7 occasions. One patient underwent retransplantation and the remaining 6
were treated conservatively. Survival was 100% in the donor lung
dysfunction group. Percent predicted forced expiratory volume in 1 second,
carbon monoxide diffusion, room air oxygen tension, and distance walked in
6 minutes were all lower (p less than 0.05) at 1 month after
transplantation in those patients with donor lung dysfunction as compared
with those without. These differences were not significant at 3 months
after transplantation. We conclude that donor lung dysfunction can usually
be managed conservatively with satisfactory results. Longer follow-up of
this group of patients will be necessary to determine the long-term
consequences of early graft injury.
ARTICLES
Management of dysfunction in the transplanted lung: experience with 7 clinical cases. Washington University Lung Transplant Group
Department of Surgery, Washington University School of Medicine, St. Louis, MO 63110.
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