The Annals of Thoracic Surgery, Vol 52, 325-326, Copyright © 1991 by The Society of Thoracic Surgeons
A new balanced operation for complex gastroesophageal reflux disease
RJ Landreneau, JB Marshall, JA Johnson, TM Boley, SR Hazelrigg, JJ Curtis and RN McClelland
Division of Cardiothoracic Surgery, University of Missouri School of Medicine, Columbia.
Twenty-seven patients with advanced gastroesophageal reflux disease have
been treated with combined transthoracic parietal cell vagotomy and
Collis-Nissen fundoplication. Gastric acid analyses (n = 20) obtained
preoperatively and 6 months postoperatively demonstrated a significant late
reduction in gastric acid output. Twenty-six patients (96%) have
experienced relief of gastroesophageal reflux disease at a mean of 13.3
months (range, 6 to 25 months) without postvagotomy symptoms. Transthoracic
parietal cell vagotomy may be considered as an adjunct to mechanical
surgical control of advanced gastroesophageal reflux disease.