HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Pogrebniak, H. W. Articles by Pass, H. I. Search for Related Content PubMed PubMed Citation Articles by Pogrebniak, H. W. Articles by Pass, H. I.

The Annals of Thoracic Surgery, Vol 52, 197-203, Copyright © 1991 by The Society of Thoracic Surgeons

ARTICLES

Reoperative pulmonary resection in patients with metastatic soft tissue sarcoma

HW Pogrebniak, JA Roth, SM Steinberg, SA Rosenberg and HI Pass
Thoracic Oncology Section, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892.

Resection of pulmonary metastases from soft tissue sarcoma has been shown to be associated with a 3-year survival of 25% to 30%. The role of multiple resections for recurrent pulmonary metastases, however, has not been clearly defined. Since 1976, 43 patients have had two or more thoracic explorations for the purpose of resecting pulmonary metastases from adult soft tissue sarcoma at our institution. In 89 reexplorations, through either median sternotomy or lateral thoracotomy, the operative mortality was 0%, and 31 of the 43 patients (72%) could be rendered free of disease at the second thoracotomy. Median survival from the second thoracotomy for the patients with resectable disease was 25 months, whereas median survival of patients who had unresectable disease was 10 months. A disease-free interval between the first and second thoracotomies of greater than 18 months was associated with prolonged survival from the second thoracotomy. Owing to lack of other therapies with proven salvage efficacy and in the absence of randomized trials, repeated thoracotomies to render patients free of disease from pulmonary soft-tissue sarcoma metastases appear justified considering the potential survival benefit and low attendant risk.

This article has been cited by other articles:

				H. N. Koong, U. Pastorino, and R. J. Ginsberg Is there a role for pneumonectomy in pulmonary metastases? Ann. Thorac. Surg., December 1, 1999; 68(6): 2039 - 2043. [Abstract] [Full Text] [PDF]

				L. Spaggiari, D. H. Grunenwald, P. Girard, P. Solli, and T. Le Chevalier Pneumonectomy for lung metastases: indications, risks, and outcome Ann. Thorac. Surg., December 1, 1998; 66(6): 1930 - 1933. [Abstract] [Full Text] [PDF]

				B. K. Temeck, L. H. Wexler, S. M. Steinberg, L. L. McClure, M. A. Horowitz, and H. I. Pass Reoperative pulmonary metastasectomy for sarcomatous pediatric histologies Ann. Thorac. Surg., September 1, 1998; 66(3): 908 - 913. [Abstract] [Full Text] [PDF]

				D. Kandioler, E. Kromer, H. Tuchler, A. End, M. R. Muller, E. Wolner, and F. Eckersberger Long-Term Results After Repeated Surgical Removal of Pulmonary Metastases Ann. Thorac. Surg., April 1, 1998; 65(4): 909 - 912. [Abstract] [Full Text] [PDF]