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The Annals of Thoracic Surgery, Vol 51, 888-892, Copyright © 1991 by The Society of Thoracic Surgeons
EW Wilkins Jr, HC Grillo, JG Scannell, AC Moncure and DJ Mathisen
Eighty-five patients operated on for thymoma from 1972 to 1989 were
evaluated, 32 with myasthenia gravis and 53 without. Masaoka staging
revealed stage I disease in 45 (53%), stage II in 23 (27%), stage III in 14
(16%), and stage IVa in 3 (4%). There was no operative mortality. Actuarial
survival at 10 years was 63.7% for all patients: 78.3% for those in stage
I, 74.7% for those in stage II, and 20.8% for those in stage III. There was
no recurrence in patients in stage I. Mediastinal recurrence developed in 4
patients in stage II considered to have noninvasive disease by the surgeon.
It is recommended that all patients be followed up for a minimum of 10
years and that all patients in stages II and III receive postoperative
radiotherapy. The presence of myasthenia gravis is no longer considered as
an adverse factor in survival.
ARTICLES
J. Maxwell Chamberlain Memorial Paper. Role of staging in prognosis and management of thymoma
Department of Surgery, Harvard Medical School, Boston, MA.
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C. Zisis, D. Rontogianni, C. Tzavara, K. Stefanaki, A. Chatzimichalis, A. Loutsidis, K. Iliadis, A. Kontaxis, T. Dosios, and I. Bellenis Prognostic Factors in Thymic Epithelial Tumors Undergoing Complete Resection Ann. Thorac. Surg., September 1, 2005; 80(3): 1056 - 1062. [Abstract] [Full Text] [PDF]
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A. A. Mangi, J. C. Wain, D. M. Donahue, H. C. Grillo, D. J. Mathisen, and C. D. Wright Adjuvant Radiation of Stage III Thymoma: Is It Necessary? Ann. Thorac. Surg., June 1, 2005; 79(6): 1834 - 1839. [Abstract] [Full Text] [PDF]
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J. L. Baran, C. M. Magro, M. A. King, T. E. Williams Jr, and P. Ross Jr Atypical thymoma: A report of seven patients Ann. Thorac. Surg., August 1, 2004; 78(2): 411 - 416. [Abstract] [Full Text] [PDF]
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F. C. Detterbeck and A. M. Parsons Thymic tumors Ann. Thorac. Surg., May 1, 2004; 77(5): 1860 - 1869. [Abstract] [Full Text] [PDF]
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F. Venuta, E. A. Rendina, F. Longo, T. De Giacomo, M. Anile, E. Mercadante, L. Ventura, M. F. Osti, F. Francioni, and G. F. Coloni Long-term outcome after multimodality treatment for stage III thymic tumors Ann. Thorac. Surg., December 1, 2003; 76(6): 1866 - 1872. [Abstract] [Full Text] [PDF]
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 M. T. Truong, B. S. Sabloff, G. W. Gladish, G. J. Whitman, and R. F. Munden Invasive Thymoma Am. J. Roentgenol., December 1, 2003; 181(6): 1504 - 1504. [Full Text] [PDF]
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S. Singhal, J. B. Shrager, D. I. Rosenthal, V. A. LiVolsi, and L. R. Kaiser Comparison of stages I-II thymoma treated by complete resection with or without adjuvant radiation Ann. Thorac. Surg., November 1, 2003; 76(5): 1635 - 1642. [Abstract] [Full Text] [PDF]
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K. Kondo and Y. Monden Therapy for thymic epithelial tumors: a clinical study of 1,320 patients from Japan Ann. Thorac. Surg., September 1, 2003; 76(3): 878 - 884. [Abstract] [Full Text] [PDF]
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A. A. Mangi, C. D. Wright, J. S. Allan, J. C. Wain, D. M. Donahue, H. C. Grillo, and D. J. Mathisen Adjuvant radiation therapy for stage II thymoma Ann. Thorac. Surg., October 1, 2002; 74(4): 1033 - 1037. [Abstract] [Full Text] [PDF]
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C. Sader, S. Sharma, and M. G. Edwards Graft-versus-host disease-type colitis: an unusual association of malignant thymoma Ann. Thorac. Surg., June 1, 2002; 73(6): 1947 - 1948. [Abstract] [Full Text] [PDF]
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Y. Refaely, D. A. Simansky, M. Paley, M. Gottfried, and A. Yellin Resection and perfusion thermochemotherapy: a new approach for the treatment of thymic malignancies with pleural spread Ann. Thorac. Surg., August 1, 2001; 72(2): 366 - 370. [Abstract] [Full Text] [PDF]
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 S. B. Johnson, T. Y. Eng, G. Giaccone, and C. R. Thomas Jr. Thymoma: Update for the New Millenium Oncologist, June 1, 2001; 6(3): 239 - 246. [Abstract] [Full Text] [PDF]
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D. Lardinois, R. Rechsteiner, R. H. Lang, M. Gugger, D. Betticher, C. von Briel, T. Krueger, and H.-B. Ris Prognostic relevance of Masaoka and Muller-Hermelink classification in patients with thymic tumors Ann. Thorac. Surg., May 1, 2000; 69(5): 1550 - 1555. [Abstract] [Full Text] [PDF]
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 G. Roviaro, F. Varoli, O. Nucca, C. Vergani, and M. Maciocco Videothoracoscopic Approach to Primary Mediastinal Pathology Chest, April 1, 2000; 117(4): 1179 - 1183. [Abstract] [Full Text] [PDF]
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I. P. Nieto, M. C. Pajuelo, and J. P. P. Robledo Reply Ann. Thorac. Surg., January 1, 2000; 69(1): 314 - 315. [Full Text] [PDF]
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 C. R. Thomas, C. D. Wright, and P. J. Loehrer Thymoma: State of the Art J. Clin. Oncol., July 1, 1999; 17(7): 2280 - 2280. [Abstract] [Full Text] [PDF]
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 M. Okumura, S. Miyoshi, Y. Takeuchi, H.-E. Yoon, M. Minami, S.-I. Takeda, Y. Fujii, K. Nakahara, and H. Matsuda Results Of Surgical Treatment Of Thymomas With Special Reference To The Involved Organs J. Thorac. Cardiovasc. Surg., March 1, 1999; 117(3): 605 - 611. [Abstract] [Full Text]
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E. A. Bacha, A. R. Chapelier, P. Macchiarini, E. Fadel, and P. G. Dartevelle Surgery for invasive primary mediastinal tumors Ann. Thorac. Surg., July 1, 1998; 66(1): 234 - 239. [Abstract] [Full Text] [PDF]
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F. Venuta, E. A. Rendina, E. O. Pescarmona, T. De Giacomo, M. L. Vegna, P. Fazi, I. Flaishman, E. Guarino, and C. Ricci Multimodality Treatment of Thymoma: A Prospective Study Ann. Thorac. Surg., December 1, 1997; 64(6): 1585 - 1591. [Abstract] [Full Text]
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J.-F. Regnard, F. Zinzindohoue, P. Magdeleinat, L. Guibert, L. Spaggiari, and P. Levasseur Results of Re-resection for Recurrent Thymomas Ann. Thorac. Surg., December 1, 1997; 64(6): 1593 - 1598. [Abstract] [Full Text]
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J.-F. Regnard, P. Magdeleinat, C. Dromer, E. Dulmet, V. De Montpreville, J.-F. Levi, and P. Levasseur PROGNOSTIC FACTORS AND LONG-TERM RESULTS AFTER THYMOMA RESECTION: A SERIES OF 307 PATIENTS J. Thorac. Cardiovasc. Surg., August 1, 1996; 112(2): 376 - 384. [Abstract] [Full Text]
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K. Yagi, T. Hirata, T. Fukuse, H. Yokomise, K. Inui, O. Ike, H. Mizuno, M. Aoki, S. Hitomi, and H. Wada Surgical Treatment for Invasive Thymoma, Especially When the Superior Vena Cava Is Invaded Ann. Thorac. Surg., February 1, 1996; 61(2): 521 - 524. [Abstract] [Full Text]
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D. Blumberg, J. L. Port, B. Weksler, R. Delgado, J. Rosai, M. S. Bains, R. J. Ginsberg, N. Martini, P. M. McCormack, V. Rusch, et al. Thymoma: A Multivariate Analysis of Factors Predicting Survival Ann. Thorac. Surg., October 1, 1995; 60(4): 908 - 913. [Abstract] [Full Text]
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J. A. Swain Myasthenia Gravis Ann. Thorac. Surg., July 1, 1995; 60(1): 223 - 224. [Full Text]
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