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The Annals of Thoracic Surgery, Vol 51, 424-429, Copyright © 1991 by The Society of Thoracic Surgeons
G Gerosa, R McKay and DN Ross
Between January 1967 and December 1988, 34 patients ranging in age from 3
to 18 years (mean, 14 +/- 3.6 years) underwent replacement of the aortic
valve or root with their own pulmonary valve. The indication for operation
was left ventricular outflow obstruction in 16 patients (47%), aortic
regurgitation in 14 (41%), mixed aortic valve disease in 3 (9%), and
failure of a previously implanted aortic homograft in 1 (3%). There were
four early deaths, all before 1971, giving a hospital mortality of 11.8%
(70% confidence interval, 6% to 20%). Surviving patients have been followed
up a cumulative total of 214 patient-years, the longest period of
observation being 16 years 8 months. Late mortality was 13.3% (70%
confidence interval, 7% to 23%), and 4 other patients required removal of
the pulmonary autograft for endocarditis. Actuarial rates at 16 years were
74% +/- 11% for freedom from reoperation on the left ventricular outflow
tract, 80% +/- 10% for freedom from reoperation on the right ventricular
outflow tract, and 77% +/- 10% for late survival. There was no instance of
primary structural degeneration in the pulmonary autograft, and all
surviving patients were in New York Heart Association functional class I
without medication. This experience demonstrates that the pulmonary
autograft can achieve good early and medium-term results in young patients.
Should growth potential be realized, it might constitute the ideal
biological valve for the left ventricular outflow in children.
ARTICLES
Replacement of the aortic valve or root with a pulmonary autograft in children
National Heart Hospital, London, England.
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