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The Annals of Thoracic Surgery, Vol 51, 215-218, Copyright © 1991 by The Society of Thoracic Surgeons
R Gaynes, B Bizek, J Mowry-Hanley and M Kirsh
We attempted to determine risk factors for nosocomial pneumonia in patients
undergoing a coronary artery bypass graft operation. We reviewed the
microbiology and medical records for any patient with a sputum culture who
had undergone a coronary artery bypass graft operation in 1988 to identify
patients with pneumonia according to a standard clinical definition. We
found 19 cases of pneumonia through our initial review; complete medical
records were found on 15 cases. Gram-negative bacilli predominated as the
most common etiologic agent causing pneumonia in this cohort. There were no
clusters noted. Mortality was 26.6%. Pneumonia occurred approximately 4
days after the operation. Thirty-six controls were randomly selected from
patients undergoing coronary artery bypass graft operations in 1988.
Logistic regression analysis revealed that a history of chronic obstructive
lung disease, duration of more than 2 days of mechanical ventilation after
operation but before diagnosis of pneumonia, and receipt of gastric acid
inhibitors (antacids or H2-blockers) were independent risk factors for
nosocomial pneumonia. Only the last risk factor was amenable to
intervention at the time of operation.
ARTICLES
Risk factors for nosocomial pneumonia after coronary artery bypass graft operations
Department of Internal Medicine, University of Michigan Hospitals, Ann Arbor.
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