|
|
||||||||
The Annals of Thoracic Surgery, Vol 49, 210-217, Copyright © 1990 by The Society of Thoracic Surgeons
NT Kouchoukos, TH Wareing, SF Murphy, C Pelate and WG Marshall Jr
Although use of one internal mammary artery (IMA) for coronary artery
bypass grafting does not appear to be associated with increased risk, the
results with both IMAs are less certain; the potential for a higher
incidence of sternal wound infection as a result of devascularization of
the sternum is a major concern. During a 42-month interval ending July
1988, 1,566 patients had coronary artery bypass grafting alone or in
combination with other procedures: 633 received only vein grafts, 687 had
unilateral IMA grafting, and 246 had bilateral IMA grafting. The IMA
patients were younger, were more often male, had better cardiac function,
and underwent fewer emergent, urgent, or combined procedures than the
patients receiving vein grafts (p less than 0.05). Thirty-day mortality was
lower among the IMA patients (unilateral IMA group, 2.8%; bilateral IMA
group, 3.7%; and vein graft group, 7.9%; p = 0.001). With the exception of
sternal wound problems, occurrence rates for postoperative complications
among the IMA patients did not differ significantly from or were lower (p
less than 0.05) than those among the patients with vein grafts. Sternal
infections occurred with greater frequency among the bilateral IMA patients
(6.9%) than among the unilateral IMA (1.9%) or vein graft (1.3%) patients
(p = 0.001). By univariate analysis, obesity, diabetes, bilateral IMA
grafting, and need for prolonged (greater than 48 hours) mechanical
ventilation were associated with a significantly higher incidence of
sternal infection (p less than 0.05).(ABSTRACT TRUNCATED AT 250 WORDS)
ARTICLES
Risks of bilateral internal mammary artery bypass grafting
Division of Cardiothoracic Surgery, Washington University School of Medicine, St. Louis, Missouri.
This article has been cited by other articles:
![]() |
D. Pevni, G. Uretzky, A. Mohr, R. Braunstein, A. Kramer, Y. Paz, I. Shapira, and R. Mohr Routine Use of Bilateral Skeletonized Internal Thoracic Artery Grafting: Long-Term Results Circulation, August 12, 2008; 118(7): 705 - 712. [Abstract] [Full Text] [PDF] |
||||
![]() |
D. Navia, M. Vrancic, G. Vaccarino, F. Piccinini, H. Raich, S. Florit, and J. Thierer Total arterial off-pump coronary revascularization using bilateral internal thoracic arteries in triple-vessel disease: surgical technique and clinical outcomes. Ann. Thorac. Surg., August 1, 2008; 86(2): 524 - 530. [Abstract] [Full Text] [PDF] |
||||
![]() |
K. Yie, C.-Y. Na, S. S. Oh, J.-H. Kim, S.-H. Shinn, and H.-J. Seo Angiographic results of the radial artery graft patency according to the degree of native coronary stenosis Eur. J. Cardiothorac. Surg., March 1, 2008; 33(3): 341 - 348. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. Zeitani, A. Penta de Peppo, A. Bianco, F. Nanni, A. Scafuri, F. Bertoldo, A. Salvati, S. Nardella, and L. Chiariello Performance of a Novel Sternal Synthesis Device After Median and Faulty Sternotomy: Mechanical Test and Early Clinical Experience Ann. Thorac. Surg., January 1, 2008; 85(1): 287 - 293. [Abstract] [Full Text] [PDF] |
||||
![]() |
Authors/Task Force Members, L. Ryden, E. Standl, M. Bartnik, G. V. d. Berghe, J. Betteridge, M.-J. de Boer, F. Cosentino, B. Jonsson, M. Laakso, et al. Guidelines on diabetes, pre-diabetes, and cardiovascular diseases: full text: The Task Force on Diabetes and Cardiovascular Diseases of the European Society of Cardiology (ESC) and of the European Association for the Study of Diabetes (EASD) Eur. Heart J. Suppl., June 1, 2007; 9(suppl_C): C3 - C74. [Full Text] [PDF] |
||||
![]() |
E. B. Savage, J. D. Grab, S. M. O'Brien, A. Ali, E. J. Okum, R. A. Perez-Tamayo, D. S. Eiferman, E. D. Peterson, F. H. Edwards, and R. S.D. Higgins Use of Both Internal Thoracic Arteries in Diabetic Patients Increases Deep Sternal Wound Infection Ann. Thorac. Surg., March 1, 2007; 83(3): 1002 - 1006. [Abstract] [Full Text] [PDF] |
||||
![]() |
D. Gabbieri, P. M. Dohmen, C. Koch, A. Lembcke, W. Rutsch, and W. Konertz Aortocoronary Endothelial Cell-Seeded Polytetrafluoroethylene Graft: 9-Year Patency Ann. Thorac. Surg., March 1, 2007; 83(3): 1166 - 1168. [Abstract] [Full Text] [PDF] |
||||
![]() |
Authors/Task Force Members, L. Ryden, E. Standl, M. Bartnik, G. Van den Berghe, J. Betteridge, M.-J. de Boer, F. Cosentino, B. Jonsson, M. Laakso, et al. Guidelines on diabetes, pre-diabetes, and cardiovascular diseases: executive summary: The Task Force on Diabetes and Cardiovascular Diseases of the European Society of Cardiology (ESC) and of the European Association for the Study of Diabetes (EASD) Eur. Heart J., January 1, 2007; 28(1): 88 - 136. [Full Text] [PDF] |
||||
![]() |
B. Gansera, F. Schmidtler, G. Gillrath, I. Angelis, K. Wenke, J. Weingartner, S. Yonden, and B. M. Kemkes Does bilateral ITA grafting increase perioperative complications? Outcome of 4462 patients with bilateral versus 4204 patients with single ITA bypass. Eur. J. Cardiothorac. Surg., August 1, 2006; 30(2): 318 - 323. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. Zeitani, A. P. de Peppo, M. Moscarelli, L. G. Wolf, A. Scafuri, P. Nardi, F. Nanni, E. Di Marzio, P. De Vico, and L. Chiariello Influence of sternal size and inadvertent paramedian sternotomy on stability of the closure site: A clinical and mechanical study J. Thorac. Cardiovasc. Surg., July 1, 2006; 132(1): 38 - 42. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. Zeitani, A. P. de Peppo, R. De Paulis, P. Nardi, A. Scafuri, S. Nardella, and L. Chiariello Benefit of Partial Right-Bilateral Internal Thoracic Artery Harvesting in Patients at Risk of Sternal Wound Complications Ann. Thorac. Surg., January 1, 2006; 81(1): 139 - 143. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. G. Raja Skeletonized bilateral internal mammary arteries in unstable angina: a paradigm shift Eur. J. Cardiothorac. Surg., November 1, 2005; 28(5): 780 - 781. [Full Text] [PDF] |
||||
![]() |
S.-W. Ryu, B.-H. Ahn, S.-J. Choo, K.-J. Na, Y.-K. Ahn, M.-H. Jeong, and S.-H. Kim Skeletonized Gastroepiploic Artery as a Composite Graft for Total Arterial Revascularization Ann. Thorac. Surg., July 1, 2005; 80(1): 118 - 123. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. G. Raja and G. D. Dreyfus Internal Thoracic Artery: To Skeletonize or Not to Skeletonize? Ann. Thorac. Surg., May 1, 2005; 79(5): 1805 - 1811. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. De Paulis, S. de Notaris, R. Scaffa, S. Nardella, J. Zeitani, C. Del Giudice, A. Penta De Peppo, F. Tomai, and L. Chiariello The effect of bilateral internal thoracic artery harvesting on superficial and deep sternal infection: The role of skeletonization J. Thorac. Cardiovasc. Surg., March 1, 2005; 129(3): 536 - 543. [Abstract] [Full Text] [PDF] |
||||
![]() |
I. Dimarakis, D. Oswal, and U. R. Nair Single stage sternal reconstruction using titanium mesh for dehiscence following open-heart surgery Interactive CardioVascular and Thoracic Surgery, February 1, 2005; 4(1): 49 - 51. [Abstract] [Full Text] [PDF] |
||||
![]() |
O. M. Bical, W. Khoury, Y. Fromes, M. Fischer, M. Sousa Uva, G. Boccara, and P. H. Deleuze Routine Use of Bilateral Skeletonized Internal Thoracic Artery Grafts in Middle-Aged Diabetic Patients Ann. Thorac. Surg., December 1, 2004; 78(6): 2050 - 2053. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. A. Mariani, A. D'Alfonso, and J. G. Grandjean Total Arterial Off-Pump Coronary Surgery: Time to Change Our Habits? Ann. Thorac. Surg., November 1, 2004; 78(5): 1591 - 1597. [Abstract] [Full Text] [PDF] |
||||
![]() |
D. G. Affleck, H. B. Barner, M. S. Bailey, L. A. Perry, H. Maniar, S. M. Prasad, and R. J. Damiano Jr Flow Dynamics of the Internal Thoracic and Radial Artery T-Graft Ann. Thorac. Surg., October 1, 2004; 78(4): 1290 - 1294. [Abstract] [Full Text] [PDF] |
||||
![]() |
Y. Deng, K. Byth, and H. S Paterson Semi-skeletonized Internal Mammary Artery Grafts and Sternal Wound Complications Asian Cardiovasc Thorac Ann, September 1, 2004; 12(3): 227 - 232. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. Verma, P. E. Szmitko, R. D. Weisel, D. Bonneau, D. Latter, L. Errett, Y. LeClerc, and S. E. Fremes Should Radial Arteries Be Used Routinely for Coronary Artery Bypass Grafting? Circulation, August 3, 2004; 110(5): e40 - e46. [Full Text] [PDF] |
||||
![]() |
C. Locker, R. Mohr, O. Lev-Ran, G. Uretzky, A. Frimerman, Y. Shaham, and I. Shapira Comparison of bilateral thoracic artery grafting with percutaneous coronary interventions in diabetic patients Ann. Thorac. Surg., August 1, 2004; 78(2): 471 - 475. [Abstract] [Full Text] [PDF] |
||||
![]() |
T. Athanasiou, M.-C. Crossman, G. Asimakopoulos, A. Cherian, A. Weerasinghe, B. Glenville, and R. Casula Should the internal thoracic artery be skeletonized? Ann. Thorac. Surg., June 1, 2004; 77(6): 2238 - 2246. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. C Groom, A. J Rassias, J. E Cormack, G. R DeFoe, C. DioDato, C. K Krumholz, R. J Forest, J. W Pieroni, B. O'Connor, C. S Warren, et al. Highest core temperature during cardiopulmonary bypass and rate of mediastinitis Perfusion, March 1, 2004; 19(2): 119 - 125. [Abstract] [PDF] |
||||
![]() |
A. A. Klesius, O. Dzemali, A. Simon, P. Kleine, U. Abdel-Rahman, C. Herzog, G. Wimmer-Greinecker, and A. Moritz Successful treatment of deep sternal infections following open heart surgery by bilateral pectoralis major flaps Eur. J. Cardiothorac. Surg., February 1, 2004; 25(2): 218 - 223. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Endo, Y. Tomizawa, and H. Nishida Bilateral Versus Unilateral Internal Mammary Revascularization in Patients With Diabetes Circulation, September 16, 2003; 108(11): 1343 - 1349. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. Muneretto, G. Bisleri, A. Negri, J. Manfredi, M. Metra, S. Nodari, and L. Dei Cas Off-pump coronary artery bypass surgery technique for total arterial myocardial revascularization: a prospective randomized study Ann. Thorac. Surg., September 1, 2003; 76(3): 778 - 783. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. K. Singh, S. K. Mishra, D. Kumar, R. D. Yadave, R. Agarwal, and S. K. Sinha Total Arterial Revascularization on Beating Heart: Experience in 803 Cases Asian Cardiovasc Thorac Ann, June 1, 2003; 11(2): 107 - 112. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. Muneretto, A. Negri, J. Manfredi, A. Terrini, G. Rodella, S. ElQarra, and G. Bisleri Safety and usefulness of composite grafts for total arterial myocardial revascularization: A prospective randomized evaluation J. Thorac. Cardiovasc. Surg., April 1, 2003; 125(4): 826 - 835. [Abstract] [Full Text] [PDF] |
||||
![]() |
Y. J. Woo and T. J. Gardner Myocardial Revascularization with Cardiopulmonary Bypass Card. Surg. Adult, January 1, 2003; 2(2003): 581 - 607. [Full Text] |
||||
![]() |
G. Rizzoli, L. Schiavon, and P. Bellini Does the use of bilateral internal mammary artery (IMA) grafts provide incremental benefit relative to the use of a single IMA graft? A meta-analysis approach Eur. J. Cardiothorac. Surg., November 1, 2002; 22(5): 781 - 786. [Abstract] [Full Text] [PDF] |
||||
![]() |
G. Prabhakar, C. K. Haan, E. D. Peterson, L. P. Coombs, J. L. Cruzzavala, and G. F. Murray The risks of moderate and extreme obesity for coronary artery bypass grafting outcomes: a study from the Society of Thoracic Surgeons' database Ann. Thorac. Surg., October 1, 2002; 74(4): 1125 - 1131. [Abstract] [Full Text] [PDF] |
||||
![]() |
L. R. Sajja and G. Mannam Right internal mammary artery and radial artery composite in situ pedicle graft in coronary artery bypass grafting Ann. Thorac. Surg., June 1, 2002; 73(6): 1856 - 1859. [Abstract] [Full Text] [PDF] |
||||
![]() |
B. Gardlund, C.Y. Bitkover, and J. Vaage Postoperative mediastinitis in cardiac surgery -- microbiology and pathogenesis Eur. J. Cardiothorac. Surg., May 1, 2002; 21(5): 825 - 830. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. E. Losanoff, B. W. Richman, and J. W. Jones Disruption and infection of median sternotomy: a comprehensive review Eur. J. Cardiothorac. Surg., May 1, 2002; 21(5): 831 - 839. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Endo, H. Nishida, Y. Tomizawa, and H. Kasanuki Benefit of Bilateral Over Single Internal Mammary Artery Grafts for Multiple Coronary Artery Bypass Grafting Circulation, October 30, 2001; 104(18): 2164 - 2170. [Abstract] [Full Text] [PDF] |
||||
![]() |
T. J. Francel and N. T. Kouchoukos A rational approach to wound difficulties after sternotomy: the problem Ann. Thorac. Surg., October 1, 2001; 72(4): 1411 - 1418. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. De Feo, R. Gregorio, A. Della Corte, C. Marra, C. Amarelli, A. Renzulli, R. Utili, and M. Cotrufo Deep sternal wound infection: the role of early debridement surgery Eur. J. Cardiothorac. Surg., June 1, 2001; 19(6): 811 - 816. [Abstract] [Full Text] [PDF] |
||||
![]() |
Y. Nakayama, R. Sakata, and M. Ura Bilateral internal thoracic artery use for dialysis patients: does it increase operative risk? Ann. Thorac. Surg., March 1, 2001; 71(3): 783 - 787. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. De Feo, A. Renzulli, G. Ismeno, R. Gregorio, A. Della Corte, R. Utili, and M. Cotrufo Variables predicting adverse outcome in patients with deep sternal wound infection Ann. Thorac. Surg., January 1, 2001; 71(1): 324 - 331. [Abstract] [Full Text] [PDF] |
||||
![]() |
B. El Nakadi, C. Choghari, and M. Joris Complete myocardial revascularization with bilateral internal thoracic artery T graft Ann. Thorac. Surg., February 1, 2000; 69(2): 498 - 500. [Abstract] [Full Text] [PDF] |
||||
![]() |
B. Korbmacher, H.H. Schmitt, G. Bauer, M. Hoffmann, H. Vosberg, O. Simic, and E. Gams Change of sternal perfusion following preparation of the internal thoracic artery - a scintigraphical study Eur. J. Cardiothorac. Surg., January 1, 2000; 17(1): 58 - 62. [Abstract] [Full Text] [PDF] |
||||
![]() |
W. E. Trick, W. E. Scheckler, J. I. Tokars, K. C. Jones, M. L. Reppen, E. M. Smith, and W. R. Jarvis MODIFIABLE RISK FACTORS ASSOCIATED WITH DEEP STERNAL SITE INFECTION AFTER CORONARY ARTERY BYPASS GRAFTING J. Thorac. Cardiovasc. Surg., January 1, 2000; 119(1): 108 - 114. [Abstract] [Full Text] [PDF] |
||||
![]() |
K. A. Eagle, R. A. Guyton, R. Davidoff, G. A. Ewy, J. Fonger, T. J. Gardner, J. P. Gott, H. C. Herrmann, R. A. Marlow, W. C. Nugent, et al. ACC/AHA guidelines for coronary artery bypass graft surgery: A report of the American College of Cardiology/ American Heart Association task force on Practice Guidelines (Committee to revise the 1991 Guidelines for Coronary Artery Bypass Graft Surgery) J. Am. Coll. Cardiol., October 1, 1999; 34(4): 1262 - 1347. [Full Text] [PDF] |
||||
![]() |
A. J. Cohen, J. Lockman, M. Lorberboym, O. Bder, N. Cohen, B. Medalion, and A. Schachner ASSESSMENT OF STERNAL VASCULARITY WITH SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY AFTER HARVESTING OF THE INTERNAL THORACIC ARTERY J. Thorac. Cardiovasc. Surg., September 1, 1999; 118(3): 496 - 502. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. Gurevitch, Y. Paz, I. Shapira, M. Matsa, A. Kramer, D. Pevni, O. Lev-Ran, Y. Moshkovitz, and R. Mohr Routine use of bilateral skeletonized internal mammary arteries for myocardial revascularization Ann. Thorac. Surg., August 1, 1999; 68(2): 406 - 411. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. R. Doty, J. D. Fonger, J. D. Salazar, P. L. Walinsky, and N. W. Salomon EARLY EXPERIENCE WITH MINIMALLY INVASIVE DIRECT CORONARY ARTERY BYPASS GRAFTING WITH THE INTERNAL THORACIC ARTERY J. Thorac. Cardiovasc. Surg., May 1, 1999; 117(5): 873 - 880. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. J. Rassias, C. A. S. Marrin, J. Arruda, P. K. Whalen, M. Beach, and M. P. Yeager Insulin Infusion Improves Neutrophil Function in Diabetic Cardiac Surgery Patients Anesth. Analg., May 1, 1999; 88(5): 1011 - 1016. [Abstract] [Full Text] [PDF] |
||||
![]() |
O. Wendler, D. Tscholl, Q. Huang, and H.-J. Schafers Free flow capacity of skeletonized versus pedicled internal thoracic artery grafts in coronary artery bypass grafts Eur. J. Cardiothorac. Surg., March 1, 1999; 15(3): 247 - 250. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. J.F. Baskett, C. E. MacDougall, and D. B. Ross Is mediastinitis a preventable complication? A 10-year review Ann. Thorac. Surg., February 1, 1999; 67(2): 462 - 465. [Abstract] [Full Text] [PDF] |
||||
![]() |
J.-M. Farinas, M. Carrier, Y. Hebert, R. Cartier, M. Pellerin, L. P. Perrault, and L. C. Pelletier Comparison of long-term clinical results of double versus single internal mammary artery bypass grafting Ann. Thorac. Surg., February 1, 1999; 67(2): 466 - 470. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. Bellchambers, J.M. Harris, P. Cullinan, H. Gaya, and J.R. Pepper A prospective study of wound infection in coronary artery surgery Eur. J. Cardiothorac. Surg., January 1, 1999; 15(1): 45 - 50. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Sousa Uva, E. Braunberger, M. Fisher, Y. Fromes, P. H. Deleuze, J. A. Celestin, and O. M. Bical Does bilateral internal thoracic artery grafting increase surgical risk in diabetic patients? Ann. Thorac. Surg., December 1, 1998; 66(6): 2051 - 2055. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. Tatoulis, B. F. Buxton, and J. A. Fuller Bilateral radial artery grafts in coronary reconstruction: technique and early results in 261 patients Ann. Thorac. Surg., September 1, 1998; 66(3): 714 - 720. [Abstract] [Full Text] [PDF] |
||||
![]() |
N. J. O. Birkmeyer, D. C. Charlesworth, F. Hernandez, B. J. Leavitt, C. A. S. Marrin, J. R. Morton, E. M. Olmstead, and G. T. O'Connor Obesity and Risk of Adverse Outcomes Associated With Coronary Artery Bypass Surgery Circulation, May 5, 1998; 97(17): 1689 - 1694. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. Y. Bitkover and B. Gardlund Mediastinitis After Cardiovascular Operations: A Case-Control Study of Risk Factors Ann. Thorac. Surg., January 1, 1998; 65(1): 36 - 40. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. Tatoulis, B. F. Buxton, and J. A. Fuller Results of 1,454 Free Right Internal Thoracic Artery-to-Coronary Artery Grafts Ann. Thorac. Surg., November 1, 1997; 64(5): 1263 - 1268. [Abstract] [Full Text] |
||||
![]() |
G. Soulez, M. Gagner, E. Therasse, F. Basile, I. Prieto, P. Pibarot, C. Laflamme, L. Lamarre, and H. Shennib Catheter-Assisted Totally Thoracoscopic Coronary Artery Bypass Grafting: A Feasibility Study Ann. Thorac. Surg., October 1, 1997; 64(4): 1036 - 1040. [Abstract] [Full Text] |
||||
![]() |
A. W. Pick, T. A. Orszulak, B. J. Anderson, and H. V. Schaff Single Versus Bilateral Internal Mammary Artery Grafts: 10-Year Outcome Analysis Ann. Thorac. Surg., September 1, 1997; 64(3): 599 - 605. [Abstract] [Full Text] |
||||