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The Annals of Thoracic Surgery, Vol 48, 60-65, Copyright © 1989 by The Society of Thoracic Surgeons
GJ Kontos Jr, HV Schaff, TA Orszulak, FJ Puga, JR Pluth and GK Danielson
Twenty-seven patients underwent reoperation because of thrombotic
obstruction of a disc-type cardiac valve prosthesis. Preoperative clinical
features included effort dyspnea in 81%, new-onset angina in 44%, a new
murmur in 89%, and an abnormal opening or closing sound associated with the
prosthetic valve in 56%. Symptoms were present for 1 week or more before
reoperation in 86%, although many patients were referred only after acute
exacerbation of heart failure and development of pulmonary edema.
Noninvasive studies confirmed prosthetic valve malfunction in only 33%, but
cardiac catheterization documented thrombotic obstruction in all 15
patients in whom it was performed. In 14 of the 27 patients, prothrombin
time was in the therapeutic range at the time of admission. Prompt
reoperation for valve replacement or thrombectomy was performed with an
operative mortality of 11%, and long- term outcome was satisfactory in all
but 1 hospital survivor. These findings emphasize the importance of
considering the diagnosis of thrombosed heart valves in patients with
mechanical heart valves who are seen with nonspecific symptoms.
ARTICLES
Thrombotic obstruction of disc valves: clinical recognition and surgical management
Section of Thoracic and Cardiovascular Surgery, Mayo Clinic, Rochester, Minnesota 55905.
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