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The Annals of Thoracic Surgery, Vol 47, 831-837, Copyright © 1989 by The Society of Thoracic Surgeons
KV Arom, DM Nicoloff, TE Kersten, WF Northrup 3d, WG Lindsay and RW Emery
Records of 1,298 consecutive patients who had received the St. Jude Medical
prosthesis were reviewed (713 male and 585 female patients; mean age, 61.79
+/- 13.4 years). Early mortality was 5.7% (74 patients). Ninety-three
percent complete follow-up was accomplished for the 1,224 patients who left
the hospital (4,306.50 patient-years). One hundred ninety-two of these
patients died, a late mortality of 16.9%. Sixty-four patients experienced
thromboembolic episodes (17 major and 35 permanent). Twenty-four patients
had anticoagulant-related bleeding, 4 had valve thrombosis, 7 had
prosthetic valve endocarditis, 9 had paravalvular leak, and 10 underwent
reoperation. There was no structural valve failure in this series.
Twenty-two of the 118 patients who had valve-related complications died;
another 15 patients died of sudden and unknown causes. Therefore, the total
number of valve-related deaths was 37. Of those patients who survived, New
York Heart Association functional class improved significantly (98% in
classes II and III preoperatively and 96% in classes I and II
postoperatively). Linearized rates for thromboembolism, valve thrombosis,
and anticoagulant-related bleeding were 1.49% +/- 0.19%, 0.09% +/- 0.05%,
and 0.56% +/- 0.11%/100 patient-years, respectively. The actuarial estimate
of incidence free from all complications, operative death, and
valve-related death was 66.9% +/- 8.2% at the end of 9 years. In spite of
old age and advanced heart disease, the patients who received the St. Jude
Medical prosthesis had very good results over a 10-year period.
ARTICLES
Ten years' experience with the St. Jude Medical valve prosthesis
Minneapolis Heart Institute, Minnesota.
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