HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Antkowiak, J. G. Articles by Takita, H. Search for Related Content PubMed PubMed Citation Articles by Antkowiak, J. G. Articles by Takita, H.

The Annals of Thoracic Surgery, Vol 47, 391-393, Copyright © 1989 by The Society of Thoracic Surgeons

ARTICLES

Bronchogenic carcinoma in patients under age 40

JG Antkowiak, AM Regal and H Takita
Department of Thoracic Surgery and Oncology, Roswell Park Memorial Institute, Buffalo, NY 14263.

Eighty-nine patients aged 19 to 39 years were treated for bronchogenic carcinoma at Roswell Park Memorial Institute between 1973 and 1983. The male to female ratio was 1.6:1. The vast majority of patients were habitual cigarette smokers. Forty-four patients (49%) had adenocarcinoma or bronchoalveolar cell carcinoma. Twenty-seven (30%) had large cell undifferentiated carcinoma. Nine (10%) had small cell carcinoma and 6 (7%), squamous cell carcinoma. At the time of diagnosis, 2 patients (2%) had stage I disease, 3 (3%) had stage II disease, 30 (34%) had stage IIIA disease, 28 (32%) had stage IIIB disease, and 26 (29%) had stage IV disease. Only 3 patients survive. Median survival of all patients was 7.5 months. Median survival of patients whose tumor was surgically resected was 17.5 months. Advanced stage of disease at the time of diagnosis characterized this group of young patients with primary cancer of the lung. The brief duration of symptoms and the poor survival suggest this is a more aggressive tumor in younger patients than in older patients.

This article has been cited by other articles:

				Y. Funakoshi, S.-i. Takeda, Y. Kadota, T. Kusu, and H. Maeda Clinical Characteristics and Surgery of Primary Lung Cancer in Younger Patients Asian Cardiovasc Thorac Ann, October 1, 2008; 16(5): 387 - 391. [Abstract] [Full Text] [PDF]

				A. S. Bryant and R. J. Cerfolio Differences in outcomes between younger and older patients with non-small cell lung cancer. Ann. Thorac. Surg., May 1, 2008; 85(5): 1735 - 1739. [Abstract] [Full Text] [PDF]

				British Thoracic Society, Society of Cardiothoracic Surgeons of Great Britai, and Ireland Working Party Guidelines on the selection of patients with lung cancer for surgery Thorax, February 1, 2001; 56(2): 89 - 108. [Full Text]

				F. Bernet, R. Brodbeck, M.-O. Guenin, G. Schupfer, J. M. Habicht, P. M. Stulz, and T. P. Carrel Age does not influence early and late tumor-related outcome for bronchogenic carcinoma Ann. Thorac. Surg., March 1, 2000; 69(3): 913 - 918. [Abstract] [Full Text] [PDF]

				S. M. Gadgeel, S. Ramalingam, G. Cummings, M. J. Kraut, A. J. Wozniak, L. E. Gaspar, and G. P. Kalemkerian Lung Cancer in Patients < 50 Years of Age: The Experience of an Academic Multidisciplinary Program Chest, May 1, 1999; 115(5): 1232 - 1236. [Abstract] [Full Text] [PDF]

				W. C. Nugent, M. T. Edney, P. G. Hammerness, B. J. Dain, L. H. Maurer, and J. R. Rigas Non-Small Cell Lung Cancer at the Extremes of Age: Impact on Diagnosis and Treatment Ann. Thorac. Surg., January 1, 1997; 63(1): 193 - 197. [Abstract] [Full Text]