ATS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Graver, L. M.
Right arrow Articles by Tyras, D. H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Graver, L. M.
Right arrow Articles by Tyras, D. H.

The Annals of Thoracic Surgery, Vol 46, 85-88, Copyright © 1988 by The Society of Thoracic Surgeons

ARTICLES

The risks and benefits of thrombolytic therapy in acute aortic and mitral prosthetic valve dysfunction: report of a case and review of the literature

LM Graver, PM Gelber and DH Tyras
Division of Cardiothoracic Surgery, Long Island Jewish Medical Center, New Hyde Park, NY 11042.

A patient with acute thrombosis of a St. Jude mitral prosthesis was treated with streptokinase with initial success. Subsequent recurrent thrombosis and embolism prompted operative revision. Because the use of thrombolytic agents in this setting is somewhat controversial, we searched the literature for all reports of aortic or mitral prosthetic valve dysfunction treated this way. The cases of 58 patients treated 62 times were reviewed for efficacy of therapy and morbidity. Thrombolytic therapy may be useful in patients with prosthetic valve thrombosis causing critical hemodynamic compromise. It is frequently the only treatment needed. Further, it may help reduce operative risk for those patients in whom complete resolution is not possible. The incidence of systemic embolism is 18%, however, neurological events are usually limited and transient.


This article has been cited by other articles:


Home page
 HeartHome page
M M Yusuf, R A Archbold, A Wood, and D Dymond
Paraprosthetic leak unmasked by thrombolysis for thrombosed mitral valve
Heart, April 1, 2004; 90(4): e18 - 18.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
J. Barbetseas, S. F. Nagueh, C. Pitsavos, P. K. Toutouzas, M. A. Quinones, and W. A. Zoghbi
Differentiating thrombus from pannus formation in obstructed mechanical prosthetic valves: an evaluation of clinical, transthoracic and transesophageal echocardiographic parameters
J. Am. Coll. Cardiol., November 1, 1998; 32(5): 1410 - 1417.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
R. Manteiga, J. C. Souto, A. Altes, J. Mateo, A. Aris, J. M Dominguez, X. Borras, F. Carreras, and J. Fontcuberta
Short-course thrombolysis as the first line of therapy for cardiac valve thrombosis
J. Thorac. Cardiovasc. Surg., April 1, 1998; 115(4): 780 - 784.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
T.-M. Lee, S.-H. Chu, L.-C. Wang, and Y.-T. Lee
Thrombolysis for Obstructed CarboMedics Mitral Valve Prosthesis
Ann. Thorac. Surg., February 1, 1995; 59(2): 509 - 511.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 1988 by The Society of Thoracic Surgeons.