HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Fujiwara, T. Articles by Kajiya, F. Search for Related Content PubMed PubMed Citation Articles by Fujiwara, T. Articles by Kajiya, F.

The Annals of Thoracic Surgery, Vol 46, 79-84, Copyright © 1988 by The Society of Thoracic Surgeons

ARTICLES

Coronary flow characteristics of left coronary artery in aortic regurgitation before and after aortic valve replacement

T Fujiwara, A Nogami, H Masaki, H Yamane, S Kanazawa, S Matsuoka, H Yoshida, T Katsumura, Y Ogasawara and F Kajiya
Department of Thoracic Surgery, Kawasaki Medical School, Japan.

In 6 patients with pure aortic regurgitation, the velocity waveform in the left anterior descending coronary artery (LAD) was measured using an 80-channel 20-MHz-pulse Doppler velocimeter before and immediately after aortic valve replacement. All patients showed normal coronary angiograms. Flow velocity was analyzed by both zero-cross and fast Fourier transform methods in real time. The LAD flow in severe aortic regurgitation was characterized by an increase in the systolic flow component, a small and rapidly decreased diastolic flow, an irregular velocity profile across the vessel, and a wider velocity spectrum. After aortic valve replacement, systolic flow decreased by 36.3 +/- 21.7% (p less than 0.01), whereas diastolic flow increased by 81.4 +/- 51.8% (p less than 0.05). The ratio of diastolic flow to total LAD flow increased from 63 +/- 13% to 82 +/- 7% (p less than 0.05). The velocity profile became more parabolic and had a narrow spectrum. These results suggest that operation for aortic regurgitation induces beneficial effects on the myocardial inflow immediately after valve replacement.

This article has been cited by other articles:

				T. Mihaljevic, M. R. Sayeed, S. C. Stamou, and S. Paul Pathophysiology of Aortic Valve Disease Card. Surg. Adult, January 1, 2008; 3(2008): 825 - 840. [Full Text]

				T. Mihaljevic, S. Paul, L. H. Cohn, and A. Wechsler Pathophysiology of Aortic Valve Disease Card. Surg. Adult, January 1, 2003; 2(2003): 791 - 810. [Full Text]