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The Annals of Thoracic Surgery, Vol 45, 548-553, Copyright © 1988 by The Society of Thoracic Surgeons
SY DeLeon, FS Idriss, MN Ilbawi, CE Duffy, DW Benson Jr and CL Backer
Fifty-three patients with transposition of the great arteries and
Taussig-Bing anomaly undergoing an arterial switch procedure were divided
into two groups. Group 1 (N = 32) received multidose cardioplegia injected
initially into the aortic root and subsequently into the coronary artery
orifices and Group 2 (N = 21), single-dose cardioplegia injected into the
aortic root. The mean aortic cross-clamp and bypass times were generally
longer in Group 1 compared with Group 2. Group 1 patients with simple
transposition undergoing primary repair (N = 15) had an aortic cross-clamp
time of 80 +/- 8 minutes and a bypass time of 203 +/- 27 minutes versus 64
+/- 6 minutes (p less than 0.001) and 170 +/- 15 minutes (p less than
0.01), respectively, for similar patients in Group 2 (N = 10). Group 1
patients with simple transposition undergoing staged repair (N = 7) had an
aortic cross- clamp time of 71 +/- 6 minutes and a bypass time of 201 +/-
24 minutes versus 66 +/- 4 minutes (p = not significant [NS]) and 226 +/-
25 minutes (p = NS), respectively, for Group 2 (N = 6). In Group 1 patients
with complex transposition (N = 10), the aortic bypass time was 79 +/- 12
minutes and the bypass time was 261 +/- 40 minutes versus 64 +/- 11 minutes
(p less than 0.05) and 225 +/- 16 minutes (p less than 0.1), respectively,
for Group 2 (N = 5). Early mortality was 16% (5/32) in Group 1; there were
no early deaths in Group 2.(ABSTRACT TRUNCATED AT 250 WORDS)
ARTICLES
Comparison of single versus multidose blood cardioplegia in arterial switch procedures
Division of Cardiovascular-Thoracic Surgery, Children's Memorial Hospital, Chicago, IL 60614.
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