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The Annals of Thoracic Surgery, Vol 45, 35-38, Copyright © 1988 by The Society of Thoracic Surgeons
AB Kaiser, DS Kernodle, NL Barg and MR Petracek
We undertook a prospective randomized observer-blinded study comparing the
ability of preoperative showers with chlorhexidine gluconate (Hibiclens),
povidone-iodine (Betadine), and a lotion soap (Safe 'N Sure) to diminish
the staphylococcal skin flora of patients. By block randomization, patients
scheduled for an elective cardiac operation or coronary artery angioplasty
were assigned to shower with one of the study skin cleansers either once
(evening only) or twice (both evening and morning) before the procedure.
Semiquantitative samples for culture were obtained from the subclavian and
inguinal sites on the evening before the procedure (baseline culture) and
again the next morning before the operation. The chlorhexidine skin
cleanser consistently reduced staphylococcal colony counts at both the
subclavian and inguinal sites before the procedure. This reduction was
significant for patients showering both evening and morning (p less than
0.05). The use of the povidone-iodine skin cleanser inconsistently affected
skin flora. Patients using lotion soap either experienced no change or had
an increase in colony counts. Chlorhexidine is more effective than
povidone-iodine in diminishing skin colonization with staphylococci in
patients before operation. Repeated applications of chlorhexidine are
superior to a single shower with this agent.
ARTICLES
Influence of preoperative showers on staphylococcal skin colonization: a comparative trial of antiseptic skin cleansers
Department of Medicine, Saint Thomas Hospital, Nashville, TN 37202.
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