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The Annals of Thoracic Surgery, Vol 43, 554-556, Copyright © 1987 by The Society of Thoracic Surgeons

ARTICLES

Occlusive coronary arteritis: a cause of early death in a cardiac transplant patient

OH Frazier, HA McAllister, CT Jammal, CT Van Buren, OU Okereke, B Radovancevic and DA Cooley

A patient died 5 months after undergoing cardiac transplantation. Endomyocardial biopsies performed prior to death showed no evidence of severe rejection. At autopsy, nonnecrotizing occlusive coronary arteritis was present. The intima of the coronary arteries contained numerous lymphocytes and plasma cells. Chronic rejection appeared to be responsible for the arteritis. The onset of coronary occlusive disease is insidious, and recognition depends on the performance of coronary arteriography, which is usually not done until the one-year follow-up. Early coronary arteriography is suggested to rule out occlusive coronary arteritis when cardiac allograft function is not satisfactory, even when the endomyocardial biopsy shows no evidence of rejection.

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