HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Mavroudis, C. Articles by Polk, H. C. Search for Related Content PubMed PubMed Citation Articles by Mavroudis, C. Articles by Polk, H. C., Jr

The Annals of Thoracic Surgery, Vol 43, 298-302, Copyright © 1987 by The Society of Thoracic Surgeons

ARTICLES

Experimental aerobic-anaerobic thoracic empyema in the guinea pig

C Mavroudis, BL Ganzel, SK Cox and HC Polk Jr

The clinical and pathological features of experimental aerobic- anaerobic thoracic empyema in the Duncan-Harley guinea pig are described. Thoracic empyema development and early death (less than 14 days after bacterial inoculation) were noted after various concentrations and species were inoculated into the pleural space with a piece of umbilical tape, which was used as a cofactor. The effect of concomitant hemothorax was also tested. Gram-negative infection was found to have a more virulent course than Gram-positive infection in the thoracic cavity. Moreover, these findings support the thesis that intrathoracic inoculation of anaerobic bacteria, even in combination with other anaerobic species, fails to produce clinical empyemas. However, anaerobic bacteria appear to enhance synergistically the virulence of sublethal and subempyema-forming concentrations of aerobic bacteria such as Staphylococcus aureus and Escherichia coli.

This article has been cited by other articles:

				C. Alexiou, A. Goyal, R. K. Firmin, and M. St. J. Hickey Is open thoracotomy still a good treatment option for the management of empyema in children? Ann. Thorac. Surg., December 1, 2003; 76(6): 1854 - 1858. [Abstract] [Full Text] [PDF]

				C. Mavroudis, M. A. Malangoni, S. L. Katzmark, R. Montgomery, C. R. Schrodt, and H. C. Polk Jr The Comparative Clearance Rates of the Pleural and Peritoneal Cavities Arch Surg, February 1, 1988; 123(2): 157 - 161. [Abstract] [PDF]