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The Annals of Thoracic Surgery, Vol 42, 27-30, Copyright © 1986 by The Society of Thoracic Surgeons
PA Spence, CM Peniston, N Mihic, TE David, AK Jabr, D Archer and TA Salerno
There is controversy regarding the optimal management of patients in whom
acute papillary muscle rupture develops. This study evaluates the effect of
division of the anterolateral papillary muscle on left ventricular (LV)
function and compares two methods of treatment--mitral valve replacement
(MVR) and mitral valve repair. Thirteen pigs were placed on cardiopulmonary
bypass, and interventions were performed in an isolated beating heart
preparation. LV function was assessed with a compliant intraventricular
balloon at baseline, after division of the anterolateral papillary muscle
(Divided), after repair of the divided papillary muscle (Repair), and
finally after MVR. Division of the anterolateral papillary muscle caused a
significant deterioration in LV function. Function was maintained at this
level after mitral valve repair but deteriorated with MVR. Developed
pressure measured at baseline was 179 +/- 13 mm Hg; Divided, 148 +/- 11 mm
Hg (p less than 0.05 versus baseline); Repair, 149 +/- 15 mm Hg; and MVR,
95 +/- 8 mm Hg (p less than 0.05 versus Divided) at a balloon volume of 20
ml. These results suggest that LV function is impaired by papillary muscle
rupture. Repair of the ruptured papillary muscle is associated with better
LV function than is MVR.
ARTICLES
A physiological approach to surgery for acute rupture of the papillary muscle
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