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The Annals of Thoracic Surgery, Vol 36, 281-288, Copyright © 1983 by The Society of Thoracic Surgeons
PA Penkoske, GR Westerman, GR Marx, M Rabinovitch, MD Freed, WI Norwood and AR Castaneda
From May, 1978, to July, 1982, 46 infants ranging in age from 12 days to 12
months and in weight from 2.1 to 8.4 kg underwent repair of
dextrotransposition of the great arteries (D-TGA) and ventricular septal
defect (VSD) using a Senning repair and closure of the VSD. Ventricular
septal defects were classified as membranous (47.8%), malaligned (28.3%),
atrioventricular (AV) canal type (13.0%), subarterial (2.2%), muscular
(2.2%), and multiple (6.5%). Hospital mortality was 15.2% and late
mortality, 5.1%. Postoperative complications included tricuspid
regurgitation (mild in 3 and severe, requiring tricuspid valve replacement,
in 3), residual VSD (pulmonary/systemic flow ratio of greater than 2:1) in
3 patients (2, AV canal type and 1, multiple VSDs), pulmonary venous
obstruction in 3 patients, and permanent complete heart block in 4 patients
(2, AV canal type of VSD also requiring tricuspid valve replacement). Lung
biopsy studies showed reversible Heath-Edwards and morphometric changes. No
patient was seen with Heath-Edwards III or greater changes. In 10 patients,
right ventricular end-diastolic pressures and pulmonary artery pressures at
rest were within normal limits one year after operation. As the operative
mortality of atrial inversion and arterial switch operations for D-TGA with
VSD tends to become comparable, more extensive follow-up data, including
cardiac catheterization and coronary arteriography in a large number of
patients, will be necessary to establish the superiority of one approach
over the other.
ARTICLES
Transposition of the great arteries and ventricular septal defect: results with the Senning operation and closure of the ventricular septal defect in infants
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