The Annals of Thoracic Surgery, Vol 33, 234-237, Copyright © 1982 by The Society of Thoracic Surgeons
Cardioplegia for severe coronary artery disease: an improved technique using direct coronary artery infusion
JG Coles, GJ Wilson, GA Tait, P Klement, JC Coles, RD Weisel and RJ Baird
Conventional techniques of cardioplegic solution administration result in
regional disparities in the level of myocardial protection in patients with
severe coronary artery disease. This report describes a simple adjunct to
conventional transaortic administration of cardioplegic solution, in which
additional solution is introduced directly through the coronary arteriotomy
used for the vein graft anastomosis. The supplemental infusate is delivered
through s small- caliber flexible catheter. This technique permits
effective perfusion of the coronary vascular bed distal to severely
stenotic and occlusive lesions. Using an experimental model of
physiologically significant coronary arterial stenosis, we compared the
effectiveness of this technique with that of conventional techniques of
cardioplegia.