The Annals of Thoracic Surgery, Vol 32, 179-187, Copyright © 1981 by The Society of Thoracic Surgeons
Clinical experience with permanent atrioventricular sequential pacing
JJ Curtis, NP Madigan, RB Whiting, KJ Mueller, AT Pezzella, JT Walls and FM Heinemann
In a 23-moth period, we implanted 26 permanent atrioventricular (AV)
sequential pacing units in 11 women and 15 men ranging from 37 to 85 years
old (mean, 68 years). Indications for pacing were complete heart block n 12
patients and sick sinus syndrome in 14 patients. Cardiac index, using
standard thermodilution techniques, was determined in 9 patients during
ventricular pacing and AV sequential pacing at constant heart rate.
Atrioventricular sequential pacing was superior in all patients, with a
mean increase in cardiac index of 22% (p greater than 0.01). Complications
of AV sequential pacing included the need to revise two pulse generator
pockets due to the large size of the pulse generator. One transvenous
atrial lead displacement occurred in a patient who had previously undergone
right atrial appendage ligation at open-heart operation. No failures of
pacing or sensing occurred during 279 patient-paced months. The theoretical
hemodynamic advantage of AV sequential pacing has been confirmed in this
clinical trial. Experience with electrode placement and improvements in
pulse generator design should aid in eliminating complications with this
pacing modality.