The Annals of Thoracic Surgery, Vol 28, 113-118, Copyright © 1979 by The Society of Thoracic Surgeons
Prophylactic coronary artery grafting in patients with few or no symptoms
CM Grondin, JG Kretz, P Vouhe, JF Tubau, L Campeau and MG Bourassa
Fifty-five patients who underwent prophylactic coronary artery grafting
were followed for 4 to 8 years. Sixteen patients had no angina, and 39 were
in New York Heart Association Functional Class I. Twenty-one patients had
single-vessel disease, 13 had double-vessel disease, and 27, triple-vessel
disease. A total of 101 grafts were inserted. There were no operative
deaths. Two patients suffered a perioperative myocardial infarction (MI),
and 3 were reoperated on for persistent bleeding. Early after operation, 9
of the 45 grafts were occluded. At 1 year, 2 patients had occlusion of all
grafts, and 1 had similar findings at 5 years. There were 4 late deaths, 3
related to coronary artery disease. Seven patients sustained a late MI.
Thirty-one of the 51 survivors (60.8%) seen late (mean, 69.3 months) after
operation were free from angina; 14 were in Class I and 6, Class II. It is
apparent from this retrospective study that patients such as these stand to
benefit little from prophylactic revascularization. Longevity may be
increased, however, in patients who are asymptomatic after MI.