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The Annals of Thoracic Surgery, Vol 25, 99-106, Copyright © 1978 by The Society of Thoracic Surgeons


ARTICLES

Tumors of the thymus and thymic region: II. Clinicopathological studies on Hodgkin's disease of the thymus

NP Bergh, P Gatzinsky, S Larsson, P Lundin and B Ridell

Among 82 patients with a tumor in the thymic region, 17 had a lesion that fulfilled the criteria for Hodgkin's disease of the thymus; the histopathological differentiation of this entity from thymomas is discussed. All patients received surgical treatment and postoperative radiotherapy. After a mean observation time of 10 years there was no local recurrence and no death due to the disease, though 3 deaths were cuased by the treatment. New clinical manifestations occurred in 3 of the 14 long-term survivors: they were treated successfully by operation or irradiation. A very aggressive surgical approach involving extirpation of all tumor tissue, extensive excision of the surrounding tissues and adjacent lymph nodes, and supplementary radiotherapy seems to be the treatment of choice.


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