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The Annals of Thoracic Surgery, Vol 20, 56-65, Copyright © 1975 by The Society of Thoracic Surgeons

ARTICLES

Isolated heart perfusion techniques for rapid screening of myocardial preservation methods. Anoxia versus ischemia

GF Tyers and HE Morgan
Department of Surgery, Pennsylvania State University College of Medicine, Hershey.

Isolated nonworking and working heart preparations are described and recent modifications that increase their reliability and scope are reviewed. Isolated perfused tissues are superior to other models for screening myocardial preservation techniques. The metabolic and functional differences between anoxia and ischemia are stressed, myocardial glycolysis is reviewed, and from basic studies potentially fruitful avenues for investigation of myocardial preservation techniques are outlined. Better application of available knowledge of myocardial metabolism could further reduce the risks of cardiac operation.


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 J. Thorac. Cardiovasc. Surg.Home page
S. S. Sett, H. Tearle, and J. G. LeBlanc
EFFECT OF GLUTAMATE-ASPARTATE REPERFUSION ON POSTISCHEMIC NEONATAL MYOCARDIUM
J. Thorac. Cardiovasc. Surg., March 1, 1997; 113(3): 462 - 466.
[Abstract] [Full Text]


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Copyright © 1975 by The Society of Thoracic Surgeons.